ArticleRSC advances2021
Preparation and characterization of sodium alginate-PVA polymeric scaffolds by electrospinning method for skin tissue engineering applications.
Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Article
- Fully Aqueous Electrospinning of Binary PVP/Sodium-Alginate and PVP/Riboflavin Nanofibres: Additive Effects and UV-Assisted Processing.Polymers · 2026Article
- A novel bioencapsulation strategy for delivering plant growth promoting bacteria via cotton seeds to improve crop yield and shelf stability.Antonie van Leeuwenhoek · 2026Review
- Fibrous Biomaterial Scaffold for Tympanic Membrane Repair: Microarchitectural Engineering and Structure Function Performance.Journal of functional biomaterials · 2026Review
- The antimicrobial peptide EM86 loaded to gamma-irradiated sodium alginate/polyvinyl alcohol electrospun nanofibrous dressing treated multidrug-resistantFrontiers in bioengineering and biotechnology · 2026Article
- Exploring of therapeutic potential of indirubin-loaded nanofibrous scaffolds for localized melanoma treatment.Journal of biological engineering · 2025Article
- Antibacterial bionanocomposite hydrogel based on hydroxyethyl cellulose, poly(vinyl alcohol), and montmorillonite clay as a scaffold for bone tissue engineering application.Scientific reports · 2025Article
- Recent advances in polymer-based drug delivery systems for atopic dermatitis: enhancing therapeutic efficacy and outcomes.Materials today. Bio · 2025Review
- Biocompatible and antibacterial co-electrospun tragacanth gum and polyaniline nanofibers for skin tissue engineering.Scientific reports · 2025Article
- Adoption of polyvinyl alcohol electrospinning materials for skin wound dressing.Journal of materials science. Materials in medicine · 2025Review
- Towards Enhanced Electrospinning of Alginate-Can Recent Strategies Overcome Limitations? A Review.Polymers · 2025Review
- Nanoparticles-incorporated hydrogel microneedle for biomedical applications: Fabrication strategies, emerging trends and future prospects.Asian journal of pharmaceutical sciences · 2025Review
- Multifunctional polymeric nanofibrous scaffolds enriched with azilsartan medoxomil for enhanced wound healing.Drug delivery and translational research · 2025Article
- Synthesis and crystal structure of piperidinyl propanenitrile towards the preparation of piperidine based bioactive films for drug delivery applications.Scientific reports · 2025Article
- Article
- A Polyurethane Electrospun Membrane Loaded with Bismuth Lipophilic Nanoparticles (BisBAL NPs): Proliferation, Bactericidal, and Antitumor Properties, and Effects on MRSA and Human Breast Cancer Cells.Journal of functional biomaterials · 2024Article
- Porous calcium silicate bioactive material-alginate composite for bone regeneration.RSC advances · 2024Article
- Research Progress of Hydrogel Microneedles in Wound Management.ACS biomaterials science & engineering · 2024Review
- The engineering, drug release, andHeliyon · 2024Article
- Three-dimensional model of normal human dermal tissue using serial tissue sections.Frontiers in bioengineering and biotechnology · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sodium alginate (SA) has proven its high potential in tissue engineering and regenerative medicine. One of the main weaknesses of this polysaccharide is its low spinnability. Nanofiber-based scaffolds are of interest to scientists for biomedical engineering. The main aim of this study was to improve the spinnability of SA in combination with polyvinyl alcohol (PVA). The main parameters in the electrospinning of the optimized SA:PVA ratio, including voltage, flow rate, and working space were also optimized. To achieve this, response surface methodology under central composite design was employed to design the experiments scientifically. The final nanofiber scaffolds were studied using scanning electron microscopy, Fourier transform infrared spectroscopy for degradability, swelling, tensile strength, porosity, nanofiber diameter, contact angle, and cytotoxicity. Based on the results, the best ratio for SA : PVA was 1 : 6.5 that was spinnable in various values for the process parameters. The fabricated scaffolds under these conditions revealed good physical, chemical, mechanical, and biological features. L929 cell lines revealed high viability during 48 h culture. The results revealed that uniform and homogeneous nanofibers with regular size distribution (166 nm) were obtained at 30 kV, 0.55 μL h
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Registered trials
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