Evidence map›Paper›PMID 35479684›Full record

ArticleRSC advances2021

Brønsted acid-promoted hydroamination of unsaturated hydrazones: access to biologically important 5-arylpyrazolines.

Han He, Ning Xu, Honglin Zhang, Bin Chen, Zhengnan Hu, Kang Guo, Jianlin Chun, Shujun Cao, Yingguang Zhu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Han HeJiangsu Key Laboratory of Pesticide Science, Department of Chemistry, College of Sciences, Nanjing Agricultural University Nanjing 210095 China ygzhu@njau.edu.cn.
Ning XuJiangsu Key Laboratory of Pesticide Science, Department of Chemistry, College of Sciences, Nanjing Agricultural University Nanjing 210095 China ygzhu@njau.edu.cn.
Honglin ZhangJiangsu Key Laboratory of Pesticide Science, Department of Chemistry, College of Sciences, Nanjing Agricultural University Nanjing 210095 China ygzhu@njau.edu.cn.ORCID https://orcid.org/0000-0002-8196-6223
Bin ChenJiangsu Key Laboratory of Pesticide Science, Department of Chemistry, College of Sciences, Nanjing Agricultural University Nanjing 210095 China ygzhu@njau.edu.cn.
Zhengnan HuJiangsu Key Laboratory of Pesticide Science, Department of Chemistry, College of Sciences, Nanjing Agricultural University Nanjing 210095 China ygzhu@njau.edu.cn.
Kang GuoJiangsu Key Laboratory of Pesticide Science, Department of Chemistry, College of Sciences, Nanjing Agricultural University Nanjing 210095 China ygzhu@njau.edu.cn.
Jianlin ChunJiangsu Key Laboratory of Pesticide Science, Department of Chemistry, College of Sciences, Nanjing Agricultural University Nanjing 210095 China ygzhu@njau.edu.cn.
Shujun CaoJiangsu Key Laboratory of Pesticide Science, Department of Chemistry, College of Sciences, Nanjing Agricultural University Nanjing 210095 China ygzhu@njau.edu.cn.
Yingguang ZhuJiangsu Key Laboratory of Pesticide Science, Department of Chemistry, College of Sciences, Nanjing Agricultural University Nanjing 210095 China ygzhu@njau.edu.cn.ORCID https://orcid.org/0000-0002-0429-6369

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel and efficient Brønsted acid-promoted hydroamination of hydrazone-tethered olefins has been developed. A variety of pyrazolines have been easily obtained in good to excellent yields with high chemo- and regioselectivity under simple and mild conditions. This method represents a straightforward, facile, and practical approach toward biologically important 5-arylpyrazolines, which are difficult to access by previously reported radical hydroamination of β,γ-unsaturated hydrazones.

Identifiers

PMID35479684
PMCPMC9033072

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.