Evidence map›Paper›PMID 35479610›Full record

ArticleComputing in cardiology2021

A Cardiac Shape Model for Segmentation Uncertainty Quantification.

Jess D Tate, Shireen Elhabian, Nejib Zemzemi, Wilson W Good, Peter van Dam, Dana H Brooks, Rob S MacLeod

Abstract read
In one paragraph

Article in Computing in cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jess D TateUniversity of Utah, Salt Lake City, UT, USA.
Shireen ElhabianUniversity of Utah, Salt Lake City, UT, USA.
Nejib ZemzemiInria Bordeaux Sud Ouest, France.
Wilson W GoodAcutus Medical, Inc, Carlsbad, CA, USA.
Peter van DamUMC Utrecht, The Netherlands.
Dana H BrooksNortheastern University, Boston, MA, USA.
Rob S MacLeodUniversity of Utah, Salt Lake City, UT, USA.

Funding

TRD - VisualizationP41GM103545 · NIGMS · UNIVERSITY OF UTAH · PI JOHNSON, CHRISTOPHER R., MACLEOD, ROB S. · 2012 to 2019
$9.7M
ShapeWorks in the CloudR01AR076120 · NIAMS · UNIVERSITY OF UTAH · PI ELHABIAN, SHIREEN YOUSSEF · 2019 to 2024
$2.7M
Center for Integrative Biomedical Computing Legacy TransitionR24GM136986 · NIGMS · UNIVERSITY OF UTAH · PI JOHNSON, CHRISTOPHER R., MACLEOD, ROB S. · 2020 to 2022
$1.6M
New 3D and 4D Image-Based Clinical Measures of Atrial Structural and Functional Remodeling in Atrial FibrillationR01HL135568 · NHLBI · UNIVERSITY OF UTAH · PI CATES, JOSHUA E, ELHABIAN, SHIREEN YOUSSEF · 2017 to 2020
$1.4M
ShapeWorksStudio: An Integrative, User-Friendly, and Scalable Suite for Shape Representation and AnalysisU24EB029011 · NIBIB · UNIVERSITY OF UTAH · PI ELHABIAN, SHIREEN YOUSSEF · 2019 to 2023
$1.4M
Integration of Uncertainty Quantification with SCIRun Bioelectric Field Simulation PipelineU24EB029012 · NIBIB · UNIVERSITY OF UTAH · PI MACLEOD, ROB S. · 2019 to 2021
$1.1M
NHLBI NIH HHS R01 HL135568NIAMS NIH HHS R01 AR076120NIBIB NIH HHS U24 EB029011NIBIB NIH HHS U24 EB029012NIGMS NIH HHS P41 GM103545NIGMS NIH HHS R24 GM136986
6 · The paper itself

Abstract

Segmentation of cardiac images is a variable component of many patient specific computational pipelines, yet its impact on simulated results are still not fully understood. A hurdle to to exploring the impact of the segmentation variability is the technical challenge of building a statistical shape model of the ventricles. In this study, we improved open our previous shape analysis by creating a unified shape model including both the epicardium and endocardium. We tested four techniques within ShapeWorks to generate a ventricular shape model: standard, multidomain, hybrid multidomain, and geodesic distance. The multidomain and hybrid multidomain generated a shape model using all eleven segmentations, and the geodesic distance method generated a shape model using a subset of four segmentations. Each of the shape models captured spatially dependent characteristics of the segmentation variability, including wall thickness, annular diameter, and basal truncation. While each of the three methods have benefits, the hybrid multidomain approach provided the most accurate shape model with fewest points and may be most useful in a majority of applications.

Identifiers

PMID35479610
PMCPMC9039803

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.