Evidence map›Paper›PMID 35479592›Full record

ArticleAnnals of gastroenterology

Outcomes of SARS-CoV-2 infection in patients with celiac disease: a multicenter research network study.

Yousaf Bashir Hadi, Amir Humza Sohail, Dhairya A Lakhani, Syeda Fatima Naqvi, Justin T Kupec, Asad Pervez

Open access · diamondAbstract read
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Prevalence of SARS-COV-2 infection and outcomes in Greek sarcoidosis patients.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2024
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. COVID-19 and celiac disease: a review.Therapeutic advances in gastroenterology · 2023
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yousaf Bashir HadiDepartment of Medicine, West Virginia University, Morgantown (Yousaf Bashir Hadi, Syeda Fatima Naqvi, Justin T. Kupec, Asad Pervez).
Amir Humza SohailDepartment of Surgery, NYU Langone, Long Island, Mineola, NY (Amir Humza Sohail).
Dhairya A LakhaniDepartment of Radiology, West Virginia University, Morgantown (Dhairya A. Lakhani), USA.
Syeda Fatima NaqviDepartment of Medicine, West Virginia University, Morgantown (Yousaf Bashir Hadi, Syeda Fatima Naqvi, Justin T. Kupec, Asad Pervez).
Justin T KupecDepartment of Medicine, West Virginia University, Morgantown (Yousaf Bashir Hadi, Syeda Fatima Naqvi, Justin T. Kupec, Asad Pervez).
Asad PervezDepartment of Medicine, West Virginia University, Morgantown (Yousaf Bashir Hadi, Syeda Fatima Naqvi, Justin T. Kupec, Asad Pervez).
West Virginia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Celiac disease (CD) is associated with an increased risk for respiratory infections and severe outcomes. No data have been reported in the scientific literature regarding the outcomes of COVID-19 in this population. The aim of this study was to report matched clinical outcomes in a large cohort of 930 patients with COVID-19 in the setting of known CD. Methods: Analysis of a multicenter research network TriNETX was performed, including COVID-19 patients aged more than 16 years. Outcomes of COVID-19-positive patients with concurrent CD were compared with a propensity-matched cohort of patients without CD. Results: A total of 341,499 patients with SARS-CoV-2 infection were identified on the research network: 930 (0.27%) with CD and 340,569 (99.73%) without CD. In the 30- and 60-day periods post SARS-CoV-2 infection, 12 (1.29%) and 13 (1.40%) deaths, respectively, were reported in the CD group. Fewer patients in the CD group reached the composite outcome of either mechanical ventilation or mortality at 60 days (risk ratio 0.58, 95% confidence interval 0.36-0.95). After propensity matching, no difference in clinical outcomes was observed. Conclusion: Our data suggest that patients with CD are not at increased risk of COVID-19-related morbidity or mortality.

Indexed as

celiac diseasemorbiditymortalitySARS-CoV-2, COVID-19

Identifiers

PMID35479592
PMCPMC8922266
OpenAlexW4213451909

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.