Simultaneous determination of Avanafil and Dapoxetine in human plasma using liquid chromatography/tandem mass spectrometry (LC-MS/MS) based on a protein precipitation technique.

Mona N Abou-Omar, Abdelaziz M Annadi, Noha M El Zahar, Ahmed O Youssef, Mohammed A Amin, Mohamed S Attia, Ekram H Mohamed

Open access · goldAbstract read

PubMed Full text at PMC Publisher

In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

1.0field-weighted citation impact, top 26% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Mona N Abou-OmarDepartment of Chemistry, Faculty of Women for Arts, Science and Education, Ain Shams University Cairo Egypt.

Abdelaziz M AnnadiChemistry Department, Faculty of Science, Ain Shams University Abbassia Cairo 11566 Egypt mohd_mostafa@sci.asu.edu.eg mohamed_sam@yahoo.com.

Noha M El ZaharPharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Ain Shams University Organization of African Unity Street, Abassia Cairo 11566 Egypt.

Ahmed O YoussefChemistry Department, Faculty of Science, Ain Shams University Abbassia Cairo 11566 Egypt mohd_mostafa@sci.asu.edu.eg mohamed_sam@yahoo.com.

Mohammed A AminDepartment of Chemistry, College of Science, Taif University P.O. BOX 11099 Taif 21944 Saudi Arabia.ORCID https://orcid.org/0000-0001-7024-8034

Mohamed S AttiaChemistry Department, Faculty of Science, Ain Shams University Abbassia Cairo 11566 Egypt mohd_mostafa@sci.asu.edu.eg mohamed_sam@yahoo.com.ORCID https://orcid.org/0000-0001-6074-7366

Ekram H MohamedPharmaceutical Chemistry Department, Faculty of Pharmacy, The British University in Egypt 11837 El Sherouk City Cairo Egypt.

Ain Shams University · EGBritish University in Egypt · EGTaif University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A rapid and selective LC-MS/MS method is described for the simultaneous assay of Avanafil and Dapoxetine in human plasma

Identifiers

PMID35479534

DOI10.1039/d1ra05492a

PMCPMC9040755

OpenAlexW3198486462

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.