Evidence map›Paper›PMID 35479481›Full record

ArticleRSC advances2021

Optimisation of a gold nanoparticle-based aptasensor integrated with image processing for the colorimetric detection of acephate using response surface methodology.

Mohd Junaedy Osman, Jahwarhar Izuan Abdul Rashid, Ong Keat Khim, Wan Md Zin Wan Yunus, Siti Aminah Mohd Noor, Noor Azilah Mohd Kasim, Victor Feizal Knight, Teoh Chin Chuang

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 5 countries.

Mohd Junaedy OsmanDepartment of Chemistry and Biology, Centre for Defence Foundation Studies, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia) Sungai Besi Camp 57000 Kuala Lumpur Malaysia ongkhim@upnm.edu.my.ORCID https://orcid.org/0000-0003-1892-823X
Jahwarhar Izuan Abdul RashidDepartment of Chemistry and Biology, Centre for Defence Foundation Studies, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia) Sungai Besi Camp 57000 Kuala Lumpur Malaysia ongkhim@upnm.edu.my.
Ong Keat KhimDepartment of Chemistry and Biology, Centre for Defence Foundation Studies, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia) Sungai Besi Camp 57000 Kuala Lumpur Malaysia ongkhim@upnm.edu.my.
Wan Md Zin Wan YunusCentre for Tropicalisation, National Defence University of Malaysia Sungai Besi Camp 57000 Kuala Lumpur Malaysia.
Siti Aminah Mohd NoorDepartment of Chemistry and Biology, Centre for Defence Foundation Studies, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia) Sungai Besi Camp 57000 Kuala Lumpur Malaysia ongkhim@upnm.edu.my.
Noor Azilah Mohd KasimDepartment of Chemistry and Biology, Centre for Defence Foundation Studies, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia) Sungai Besi Camp 57000 Kuala Lumpur Malaysia ongkhim@upnm.edu.my.ORCID https://orcid.org/0000-0001-7034-304X
Victor Feizal KnightResearch Centre for Chemical Defence, National Defence University of Malaysia Sungai Besi Camp 57000 Kuala Lumpur Malaysia.ORCID https://orcid.org/0000-0003-0060-4931
Teoh Chin ChuangEngineering Research Center, Malaysian Agricultural Research and Development Institute (MARDI) Malaysia.
National Defence University of Malaysia · MYFinnish Defence Forces · FIMalaysian Agricultural Research and Development Institute · MYOrganization for Tropical Studies · CR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acephate (Ac) is an organophosphate (OP) compound, which is able to inhibit the activity of acetylcholinesterase. Thus, the aim of this study was to optimize the detection of Ac using a thiolated acephate binding aptamer-citrate capped gold nanoparticle (TABA-Cit-AuNP) sensor that also incorporated an image processing technique. The effects of independent variables, such as the incubation period of TABA-Cit-AuNPs (3-24 h) for binding TABA to Cit-AuNPs, the concentration of phosphate buffer saline (PBS) (0.001-0.01 M), the concentration of thiolated acephate binding aptamer (TABA) (50-200 nM), and the concentration of magnesium sulphate (MgSO

Identifiers

PMID35479481
PMCPMC9037117
OpenAlexW3186455341

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.