Evidence map›Paper›PMID 35479455›Full record

ArticleRSC advances2021

A pH-sensitive and sustained-release oral drug delivery system: the synthesis, characterization, adsorption and release of the xanthan gum-

Li Li, Xiyan Zheng, Chunjiao Pan, Hao Pan, Zhongqiu Guo, Bingmi Liu, Yu Liu

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Mucoadhesive carriers for oral drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2022
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Li LiSchool of Pharmacy, Liaoning University Shenyang 110036 China lnuliuyu@163.com.ORCID https://orcid.org/0000-0001-9355-7059
Xiyan ZhengSchool of Pharmacy, Liaoning University Shenyang 110036 China lnuliuyu@163.com.
Chunjiao PanSchool of Pharmacy, Liaoning University Shenyang 110036 China lnuliuyu@163.com.
Hao PanSchool of Pharmacy, Liaoning University Shenyang 110036 China lnuliuyu@163.com.ORCID https://orcid.org/0000-0002-4432-3835
Zhongqiu GuoSchool of Pharmacy, Liaoning University Shenyang 110036 China lnuliuyu@163.com.
Bingmi LiuSchool of Pharmacy, Liaoning University Shenyang 110036 China lnuliuyu@163.com.
Yu LiuSchool of Pharmacy, Liaoning University Shenyang 110036 China lnuliuyu@163.com.ORCID https://orcid.org/0000-0003-2444-3079
Liaoning University · CNShenyang Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, graphene oxide (GO) was successfully prepared using the improved Hummers method, and the prepared GO powder was dissolved in distilled water and subjected to ultrasonic stripping. Diclofenac potassium (DCFP) was selected as a model drug to systematically evaluate the adsorption mechanism of DCFP by GO. Different reaction models were constructed to fit the adsorption kinetics and adsorption isotherms of DCFP on GO, in order to further explore the underlying adsorption mechanism. The results demonstrated that the pseudo-second-order kinetic model and Freundlich model could better delineate the adsorption process of DCFP by GO. Both π-π stacking and hydrophobic interaction were mainly involved in the adsorption process, and there were electrostatic interaction and hydrogen bonding at the same time. Then, the xanthan gum-

Identifiers

PMID35479455
PMCPMC9037311
OpenAlexW3190774297

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.