Evidence map›Paper›PMID 35479145›Full record

ArticleRSC advances2021

About the mechanism of ultrasonically induced protein capsule formation.

Ulrike Doering, Dmitry Grigoriev, Kosti Tapio, Sophia Rosencrantz, Ruben R Rosencrantz, Ilko Bald, Alexander Böker

Abstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ulrike DoeringInstitute of Chemistry, University of Potsdam Karl-Liebknecht-Str. 24-25 14476 Potsdam Germany.
Dmitry GrigorievFraunhofer Institute for Applied Polymer Research IAP Geiselbergstr. 69 14476 Potsdam Germany dmitry.grigoriev@iap.fraunhofer.de.ORCID https://orcid.org/0000-0001-6961-1000
Kosti TapioInstitute of Chemistry, University of Potsdam Karl-Liebknecht-Str. 24-25 14476 Potsdam Germany.
Sophia RosencrantzFraunhofer Institute for Applied Polymer Research IAP Geiselbergstr. 69 14476 Potsdam Germany dmitry.grigoriev@iap.fraunhofer.de.
Ruben R RosencrantzFraunhofer Institute for Applied Polymer Research IAP Geiselbergstr. 69 14476 Potsdam Germany dmitry.grigoriev@iap.fraunhofer.de.ORCID https://orcid.org/0000-0003-4272-128X
Ilko BaldInstitute of Chemistry, University of Potsdam Karl-Liebknecht-Str. 24-25 14476 Potsdam Germany.ORCID https://orcid.org/0000-0002-6683-5065
Alexander BökerInstitute of Chemistry, University of Potsdam Karl-Liebknecht-Str. 24-25 14476 Potsdam Germany.ORCID https://orcid.org/0000-0002-5760-6631

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, we propose a consistent mechanism of protein microcapsule formation upon ultrasound treatment. Aqueous suspensions of bovine serum albumin (BSA) microcapsules filled with toluene are prepared by use of high-intensity ultrasound following a reported method. Stabilization of the oil-in-water emulsion by the adsorption of the protein molecules at the interface of the emulsion droplets is accompanied by the creation of the cross-linked capsule shell due to formation of intermolecular disulfide bonds caused by highly reactive species like superoxide radicals generated sonochemically. The evidence for this mechanism, which until now remained elusive and was not proven properly, is presented based on experimental data from SDS-PAGE, Raman spectroscopy and dynamic light scattering.

Identifiers

PMID35479145
PMCPMC9031429

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.