Evidence map›Paper›PMID 35479104›Full record

ArticleACS measurement science au2022

Efficient Simulation of Arbitrary Multicomponent First-Order Binding Kinetics for Improved Assay Design and Molecular Assembly.

Kyle Briggs, Mohamed Yassine Bouhamidi, Liqun He, Vincent Tabard-Cossa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS measurement science au, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kyle BriggsDepartment of Physics, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.ORCID https://orcid.org/0000-0002-0183-6585
Mohamed Yassine BouhamidiDepartment of Physics, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.
Liqun HeDepartment of Physics, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.ORCID https://orcid.org/0000-0002-7417-448X
Vincent Tabard-CossaDepartment of Physics, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.ORCID https://orcid.org/0000-0003-4375-717X
University of Ottawa · CA

Funding

Solid-state nanopores and silicon nanomembranes for ultrasensitive protein biomarker detectionR01EB031581 · NIBIB · UNIVERSITY OF ROCHESTER · PI FLAX, JONATHAN D, GODIN, MICHEL · 2021 to 2024
$1.7M
NIBIB NIH HHS R01 EB031581
6 · The paper itself

Abstract

Traditional enzyme-linked immunosorbent assay (ELISA), long the workhorse for specific target protein detection using microplate wells, is nearing its fundamental limit of sensitivity. New opportunities in health care call for

Identifiers

PMID35479104
PMCPMC9026241
OpenAlexW3215970349

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.