Evidence map›Paper›PMID 35479068›Full record

ArticleFrontiers in immunology2022

Distinct Role of TNFR1 and TNFR2 in Protective Immunity Against

Yuejin Liang, James Fisher, Casey Gonzales, Brandon Trent, Galen Card, Jiaren Sun, Alexei V Tumanov, Lynn Soong

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Infection and drug resistance · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Histone MethyltransferaseAntioxidants (Basel, Switzerland) · 2022
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yuejin LiangDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
James FisherDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Casey GonzalesDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, United States.
Brandon TrentDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, United States.
Galen CardDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, United States.
Jiaren SunDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Alexei V TumanovDepartment of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Lynn SoongDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
The University of Texas Medical Branch at Galveston · USThe University of Texas Health Science Center at San Antonio · US

Funding

EMERGING AND TROPICAL INFECTIOUS DISEASEST32AI007526 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI SOONG, LYNN · 1997 to 2025
$3.1M
Pathogenic Mechanisms of Vascular Dysfunction in Scrub TyphusR01AI132674 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Yuejin Liang, LYNN SOONG · 2018 to 2026
$3.0M
Neutrophil-Mediated Bacterial Dissemination and Host Immunopathogenesis in a Murine Scrub Typhus ModelR21AI153586 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI LIANG, YUEJIN · 2020 to 2021
$435k
Mincle and STING Activation in Proinflammatory Responses to Orientia InfectionR21AI156536 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SOONG, LYNN · 2021 to 2022
$435k
T-Cell Quality and Protective Immunity in a Murine Scrub Typhus ModelR21AI126343 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SOONG, LYNN · 2016 to 2017
$426k
NIAID NIH HHS R01 AI132674NIAID NIH HHS R21 AI126343NIAID NIH HHS R21 AI153586NIAID NIH HHS R21 AI156536NIAID NIH HHS T32 AI007526
6 · The paper itself

Abstract

Infection with

Indexed as

Orientia tsutsugamushiReceptors, Tumor Necrosis Factor, Type IReceptors, Tumor Necrosis Factor, Type IIScrub TyphusAnimalsMiceMice, Inbred C57BLReceptors, Tumor Necrosis Factor, Type IReceptors, Tumor Necrosis Factor, Type IITnfrsf1a protein, mouseTnfrsf1b protein, mouseCD8Orientia tsutsugamushiT cellsTNFTNFR1TNFR2

Identifiers

PMID35479068
PMCPMC9035742
OpenAlexW4223619271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.