Evidence map›Paper›PMID 35479013›Full record

ArticleRSC advances2021

Development of biodegradable zein-based bilayer coatings for drug-eluting stents.

Martina Lenzuni, Giulia Suarato, Dalila Miele, Riccardo Carzino, Marco Ruggeri, Rosalia Bertorelli, Giuseppina Sandri, Athanassia Athanassiou

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Research progress of absorbable stents.International journal of medical sciences · 2024
    Review
  6. Article
  7. Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Martina LenzuniSmart Materials Group, Istituto Italiano di Tecnologia via Morego 30 16163 Genoa Italy martina.lenzuni@iit.it.ORCID https://orcid.org/0000-0002-2005-5389
Giulia SuaratoSmart Materials Group, Istituto Italiano di Tecnologia via Morego 30 16163 Genoa Italy martina.lenzuni@iit.it.
Dalila MieleDepartment of Drug Sciences, University of Pavia viale Taramelli 12 27100 Pavia Italy.
Riccardo CarzinoSmart Materials Group, Istituto Italiano di Tecnologia via Morego 30 16163 Genoa Italy martina.lenzuni@iit.it.
Marco RuggeriDepartment of Drug Sciences, University of Pavia viale Taramelli 12 27100 Pavia Italy.
Rosalia BertorelliTranslational Pharmacology, Istituto Italiano di Tecnologia via Morego 30 16163 Genoa Italy.
Giuseppina SandriDepartment of Drug Sciences, University of Pavia viale Taramelli 12 27100 Pavia Italy.
Athanassia AthanassiouSmart Materials Group, Istituto Italiano di Tecnologia via Morego 30 16163 Genoa Italy martina.lenzuni@iit.it.
Italian Institute of Technology · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-eluting stents (DES) have been widely used for the treatment of cardiovascular diseases. Nevertheless, chronic inflammation and delayed re-endothelialization still represent challenges for their clinical use. In the present work, we developed novel bilayer coatings for stent applications that could overcome these limitations, exclusively using biodegradable plant-based drugs and polymers. In particular, stainless steel surfaces were coated with rutin-loaded zein (the active layer) and cross-linked alginate (the sacrificial layer)

Identifiers

PMID35479013
PMCPMC9036829
OpenAlexW3183572846

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.