Evidence map›Paper›PMID 35478849›Full record

ArticleFrontiers in neuroscience2022

Cerebral Blood Flow Hemispheric Asymmetry in Comatose Adults Receiving Extracorporeal Membrane Oxygenation.

Thomas W Johnson, Irfaan A Dar, Kelly L Donohue, Yama Y Xu, Esmeralda Santiago, Olga Selioutski, Mark A Marinescu, Ross K Maddox, Tong Tong Wu, Giovanni Schifitto and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Thomas W JohnsonDepartment of Neurology, University of Rochester Medical Center, Rochester, NY, United States.
Irfaan A DarDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, United States.
Kelly L DonohueDepartment of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Yama Y XuSchool of Arts and Sciences, University of Rochester, Rochester, NY, United States.
Esmeralda SantiagoSchool of Arts and Sciences, University of Rochester, Rochester, NY, United States.
Olga SelioutskiDepartment of Neurology, University of Rochester Medical Center, Rochester, NY, United States.
Mark A MarinescuDepartment of Medicine, University of Rochester Medical Center, Rochester, NY, United States.
Ross K MaddoxDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, United States.
Tong Tong WuDepartment of Biostatistics and Computational Biology, University of Rochester, Rochester, NY, United States.
Giovanni SchifittoDepartment of Neurology, University of Rochester Medical Center, Rochester, NY, United States.
Igor GosevDivision of Cardiac Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY, United States.
Regine ChoeDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, United States.
Imad R KhanDepartment of Neurology, University of Rochester Medical Center, Rochester, NY, United States.
University of Rochester Medical Center · USUniversity of Rochester · USNorthwestern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral veno-arterial extracorporeal membrane oxygenation (ECMO) artificially oxygenates and circulates blood retrograde from the femoral artery, potentially exposing the brain to asymmetric perfusion. Though ECMO patients frequently experience brain injury, neurologic exams and imaging are difficult to obtain. Diffuse correlation spectroscopy (DCS) non-invasively measures relative cerebral blood flow (rBF) at the bedside using an optical probe on each side of the forehead. In this study we observed interhemispheric rBF differences in response to mean arterial pressure (MAP) changes in adult ECMO recipients. We recruited 13 subjects aged 21-78 years (7 with cardiac arrest, 4 with acute heart failure, and 2 with acute respiratory distress syndrome). They were dichotomized

Indexed as

cerebral blood flowcerebrovascular autoregulationcomadiffuse correlation spectroscopyextracorporeal membrane oxygenation

Identifiers

PMID35478849
PMCPMC9036108
OpenAlexW4223554127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.