Evidence map›Paper›PMID 35478398›Full record

ArticleInternational ophthalmology2022

Electrodiagnostic signs of carpal tunnel syndrome in ocular pseudoexfoliation syndrome.

Mansoor Shahriari, Afshin Karimzadeh, Hadi Esmaily, Saman Rezanejad, Homayoun Nikkhah, Maryam Yadgari, Asma Pourhoseingholi

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in International ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06946030 (The Relationship Between Ocular Pseudoexfoliation Syndrome and Carpal Tunnel Syndrome), which is not on this map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06946030 completednot on this mapstarted 2025, after this paper: background citation

The Relationship Between Ocular Pseudoexfoliation Syndrome and Carpal Tunnel Syndrome

TypeobservationalSponsorAnkara Training and Research HospitalRan2025 to 2026Enrolled159ConditionsPseudoexfoliation Syndrome, Carpal Tunnel Syndrome (CTS)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mansoor ShahriariImam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-0519-7909
Afshin KarimzadehImam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Karimzadeh@sbmu.ac.ir.ORCID https://orcid.org/0000-0003-0709-0742
Hadi EsmailyImam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Esmaily_hadi@sbmu.ac.ir.ORCID https://orcid.org/0000-0001-6915-6028
Saman RezanejadImam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Homayoun NikkhahImam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Maryam YadgariImam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-0829-1861
Asma PourhoseingholiPrevention of Cardiovascular Disease Research Center, Imam Hussein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-4380-6453
Imam Hossein Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the occurrence and severity of electrodiagnostic signs of carpal tunnel syndrome (ED-CTS) in patients with ocular pseudoexfoliation (PEX) and compare them with normal subjects.

methodA cross-sectional study with comparison group was designed and 60 patients with PEX were recruited from May 2019 to February 2021, and the findings were compared with 59 healthy subjects. All patients underwent complete ophthalmologic examination and nerve conduction velocity test at the median nerve was used to assess the occurrence and severity of ED-CTS in both hands.

resultsThe mean age of participants was 59.8 ± 4.5 years. Occurrence of ED-CTS was 38.3% in PEX patients and 20.3% in control subjects (P = 0.025). There was also a significant difference in the severityand presence of asymptomatic CTS (P < 0.05). Adjusting other variables, including; age and sex, having severe ED-CTS showed a 3.07fold higher chance in the PEX group (P = 0.005).

conclusionAccording to our finding, it seems there is a direct association between PEX and the occurrence, as well as severity of ED-CTS.

Indexed as

Carpal Tunnel SyndromeExfoliation SyndromeCross-Sectional StudiesElectrodiagnosisHumansMiddle AgedNeural ConductionCarpal tunnel syndromeNeural conductionNeuropathyPseudoexfoliation syndrome

Identifiers

PMID35478398
OpenAlexW4225108951

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.