ArticleMicrobiologyOpen2022
Combining in vitro and in vivo screening to identify efficient Pseudomonas biocontrol strains against the phytopathogenic bacterium Ralstonia solanacearum.
Article in MicrobiologyOpen, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Microgravity effects on secondary metabolism of plant-affecting bacteria.Microbiology spectrum · 2026Article
- Mechanisms of action and biocontrol potential ofFrontiers in fungal biology · 2026Review
- Microbial Metabolites: A Sustainable Approach to Combat Plant Pests.Metabolites · 2025Review
- Biotic Stress Alleviation in Plant Using Rhizobacteria: An Overview of Mechanism of Action, Antimicrobial Compounds Production, (Nano) Formulations and Employment Methods.Indian journal of microbiology · 2025Review
- Fungal Biocontrol Agents in the Management of Postharvest Losses of Fresh Produce-A Comprehensive Review.Journal of fungi (Basel, Switzerland) · 2025Review
- Antibacterial, Herbicidal, and Plant Growth-Promoting Properties ofMicroorganisms · 2024Article
- Evaluation of Resistance Induction Promoted by Bioactive Compounds ofMicroorganisms · 2024Article
- Naringenin restricts the colonization and growth of Ralstonia solanacearum in tobacco mutant KCB-1.Plant physiology · 2024Article
- Resistance towards and biotransformation of a Pseudomonas-produced secondary metabolite during community invasion.The ISME journal · 2024Article
- HarnessingFrontiers in microbiology · 2024Review
- Collaborative impact of bacterial exometabolites governing root microbiota formation.Stress biology · 2023Article
- Genome mining of3 Biotech · 2023Article
- Cofunctioning of bacterial exometabolites drives root microbiota establishment.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Deciphering key factors in pathogen-suppressive microbiome assembly in the rhizosphere.Frontiers in plant science · 2023Review
- Seaweed as a Natural Source against Phytopathogenic Bacteria.Marine drugs · 2022Review
- Combining in vitro and in vivo screening to identify efficient Pseudomonas biocontrol strains against the phytopathogenic bacterium Ralstonia solanacearum.MicrobiologyOpen · 2022Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although plant pathogens are traditionally controlled using synthetic agrochemicals, the availability of commercial bactericides is still limited. One potential control strategy could be the use of plant growth-promoting bacteria (PGPB) to suppress pathogens via resource competition or the production of antimicrobial compounds. This study aimed to conduct in vitro and in vivo screening of eight Pseudomonas strains against Ralstonia solanacearum (the causative agent of bacterial wilt) and to investigate underlying mechanisms of potential pathogen suppression. We found that inhibitory effects were Pseudomonas strain-specific, with strain CHA0 showing the highest pathogen suppression. Genomic screening identified 2,4-diacetylphloroglucinol, pyoluteorin, and orfamides A and B secondary metabolite clusters in the genomes of the most inhibitory strains, which were investigated further. Although all these compounds suppressed R. solanacearum growth, only orfamide A was produced in the growth media based on mass spectrometry. Moreover, orfamide variants extracted from Pseudomonas cultures showed high pathogen suppression. Using the "Micro-Tom" tomato cultivar, it was found that CHA0 could reduce bacterial wilt disease incidence with one of the two tested pathogen strains. Together, these findings suggest that a better understanding of Pseudomonas-Ralstonia interactions in the rhizosphere is required to successfully translate in vitro findings into agricultural applications.
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