Evidence map›Paper›PMID 35478274›Full record

ArticleMedical oncology (Northwood, London, England)2022

Controversy of tissue-agnostic approvals in immunotherapy and targeted therapy.

Chinmoy K Bose

Abstract read
PubMed Publisher
In one paragraph

Article in Medical oncology (Northwood, London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Chinmoy K BoseDepartment of Gynecologic Oncology & Department of Clinical Trial & Research, Netaji Subhas Chandra Bose Cancer Hospital, 3081, Nayabad Avenue, 8D, Mathur Sen Garden Lane, Kolkata, 700094, India. ck.bose@nscri.in.ORCID http://orcid.org/0000-0002-5416-0945

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, approval of some immunotherapy based on markers such as dMMR, tumour mutational burden and other few such markers is not received well as shown in post-approval data published. The context of such approvals and controversies is discussed briefly.

Indexed as

ImmunotherapyNeoplasmsBiomarkers, TumorHumansImmunologic FactorsBiomarkers, TumorImmunologic FactorsDeficient mismatch repair (dMMR)Immune checkpoint inhibitor (ICI)Microsatellite instability (MSI)NTRKPembrolizumabTumour mutational burden (TMB)

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.