Evidence map›Paper›PMID 35478212›Full record

ArticleScientific reports2022

Impact of disabled circadian clock on yellow fever mosquito Aedes aegypti fitness and behaviors.

Vinaya Shetty, Jacob I Meyers, Ying Zhang, Christine Merlin, Michel A Slotman

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Time-of-day modulation in mosquito response persistence to carbon dioxide is controlled by Pigment-Dispersing Factor.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Post-biting behavioral reprogramming underlies reproductive efficiency inbioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Circadian and daily rhythms of disease vector mosquitoes.Current opinion in insect science · 2024
    Review
  14. Article
  15. Review
  16. Review
  17. Identification of CYCLE targets that contribute diverse features of circadian rhythms in the mosquito Culex pipiens.Comparative biochemistry and physiology. Part D, Genomics & proteomics · 2023
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vinaya Shetty *Department of Entomology, Texas A&M University, College Station, TX, 77843, USA. vshetty@tamu.edu.
Jacob I Meyers *Department of Entomology, Texas A&M University, College Station, TX, 77843, USA.
Ying ZhangDepartment of Biology, Texas A&M University, College Station, TX, 77843, USA.
Christine MerlinDepartment of Biology, Texas A&M University, College Station, TX, 77843, USA.
Michel A SlotmanDepartment of Entomology, Texas A&M University, College Station, TX, 77843, USA.
Texas A&M University · US

Funding

Mechanisms of Circadian RepressionR01GM124617 · NIGMS · TEXAS A&M UNIVERSITY · PI PAUL E HARDIN, Christine Merlin · 2017 to 2026
$2.7M
The role of the circadian clock in the behavior of the malaria mosquito Anopheles coluzziiR21AI149100 · NIAID · TEXAS A&M AGRILIFE RESEARCH · PI ADELMAN, ZACH N. · 2020 to 2021
$415k
The genetics of behavioral resistance in Anopheles gambiae (M)R21AI115175 · NIAID · TEXAS A&M AGRILIFE RESEARCH · PI SLOTMAN, MICHEL A · 2015 to 2016
$397k
NIAID NIH HHS R21 AI115175NIAID NIH HHS R21 AI149100NIGMS NIH HHS R01 GM124617NIH HHS R01 GM124617NIH HHS R21 AI115175
6 · The paper itself

Abstract

Like other insects, Aedes aegypti displays strong daily patterns in host seeking and mating. Much of these behaviors are believed to be under the control of a circadian clock, an endogenous timekeeping mechanism relying on transcriptional/translational negative feedback loops that drive rhythmic physiology and behavior. To examine the connection between the circadian clock and various Ae. aegypti behaviors, we knocked out the core clock gene cycle using CRISPR/Cas9. We found that the rhythmic pattern and intensity of mRNA expression of seven circadian genes, including AeCyc

Indexed as

AedesCircadian ClocksYellow FeverAnimalsCircadian RhythmFemaleMosquito Vectors

Identifiers

PMID35478212
PMCPMC9046260
OpenAlexW4225097850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.