Evidence map›Paper›PMID 35478163›Full record

ArticleIn vivo (Athens, Greece)

Topical Prevention of Radiation Dermatitis in Head and Neck Cancer Patients: A Network Meta-analysis.

Yung-Shuo Kao, Kevin Sheng-Kai Ma, Min-You Wu, Yao-Cheng Wu, Yu-Kang Tu, Cheng-Hsien Hung

Open access · diamondAbstract readNetwork Meta-Analysis
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Radiomitigators: Breakthroughs in Post-Radiation Recovery.Antioxidants (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Evolution of radiation-induced dermatitis treatment.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Review
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  11. Review
  12. Article
  13. Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yung-Shuo KaoDepartment of Radiation Oncology, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Kevin Sheng-Kai MaCenter for Global Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, U.S.A.
Min-You WuSchool of Medicine, Chung Shan Medical University, Taichung, Taiwan, R.O.C.
Yao-Cheng WuSchool of Medicine, Chung Shan Medical University, Taichung, Taiwan, R.O.C.
Yu-Kang TuInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan, R.O.C.
Cheng-Hsien HungDepartment of Pharmacy, Chang Bing Show Chwan Memorial Hospital, Changhua, Taiwan, R.O.C. chenghsien823@gmail.com.
Chung Shan Medical University · TWChina Medical University · TWNational Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimHead and neck cancer is a major malignancy worldwide. The treatment strategy for head and neck cancer usually involves radiotherapy. The main side effect of radiotherapy is radiation dermatitis. Thus, determining the most effective topical regimen for the prevention of radiation dermatitis in head and neck cancer patients is a critical issue. PATIENTS AND

methodsPRISMA-NMA guidelines were used in this network meta-analysis. We included only randomized control trials. A random effects model was used. Heterogeneity was evaluated by I

resultsWe included a total of 1,304 patients in the network meta-analysis. Among them, olive oil was the only effective regimen when compared with usual care (OR=0.18, 95%CI=0.03-0.95). The I

conclusionOlive oil was the most effective regimen for the prevention of radiation dermatitis.

Indexed as

Head and Neck NeoplasmsRadiodermatitisHumansOlive OilOlive Oilhead and neck cancermeta-analysisradiation dermatitisRadiotherapy

Identifiers

PMID35478163
PMCPMC9087072
OpenAlexW4225087946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.