Evidence map›Paper›PMID 35478040›Full record

ArticleJournal of biomedical optics2022

Imaging of the skin microvascularization using spatially depolarized dynamic speckle.

Elise Colin, Aurélien Plyer, Muriel Golzio, Nicolas Meyer, Gilles Favre, Xavier Orlik

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elise ColinParis Saclay University, DTIS, ONERA, Palaiseau, France.
Aurélien PlyerParis Saclay University, DTIS, ONERA, Palaiseau, France.
Muriel GolzioCNRS IPBS, UMR 5089, Toulouse, France.
Nicolas MeyerIUC et CHU de Toulouse, Toulouse, France.
Gilles FavreCentre de Recherches en Cancérologie de Toulouse, Inserm UMR1037, CNRS UMR5071, Université Toulouse, France.
Xavier OrlikITAE Medical Research, Pechabou, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

significanceWe propose a technique devoted to real-time high-resolution imaging of skin microvascularization.

aimThe process utilizes the temporal variation of the spatially depolarized optical speckle field generated by moving red blood cells when illuminated with fully polarized coherent light. APPROACH: Polarimetric filtering prevents the contribution of surface scattering from reaching the camera and thus favors the detection of multiscattered photons from the deeper layers of the skin.

resultsFull-field images reveal the microvasculature with a spatial resolution of 80  μm. The acquisition speed allows for real-time applications.

conclusionsWe demonstrate the ability of this method to determine in 1 s a stable and reliable microvascular activity, enabling numerous clinical applications that require quantitative measurements.

Indexed as

Diagnostic ImagingSkinErythrocyte CountErythrocytescoherent imagingdermatologydynamic specklelaserpolarizationskin

Identifiers

PMID35478040
PMCPMC9043838

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.