Evidence map›Paper›PMID 35477920›Full record

ArticleNeurosciences (Riyadh, Saudi Arabia)2022

Association between obesity during different age periods and multiple sclerosis in Saudi Arabia: A multicenter case-control study.

Osama A Al-Wutayd, Ashri G Mohamed, Jameelah A Saeedi, Hessa S Alotaibi, Mohammed A Al Jumah

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurosciences (Riyadh, Saudi Arabia), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Osama A Al-WutaydFrom the Department of Family and Community Medicine (Al-Wutayd), Unaizah College of Medicine and Medical Sciences, Qassim University, Unaizah, Department of Family and Community Medicine Department (Mohamed), King Khalid University Hospital, King Abdullah bin Abdul-Aziz University Hospital (Saeedi), Princess Nora bint Abdulrahman University, King Fahad Medical City (Al Jumah), Ministry of Health, King Abdullah International Medical Research Center-King Saud bin Abdulaziz University for Health Sciences (Al Jumah), Riyadh, and from King Fahad General Hospital (Alotaibi), Ministry of Health, Jedda, Kingdom of Saudi Arabia.
Ashri G MohamedFrom the Department of Family and Community Medicine (Al-Wutayd), Unaizah College of Medicine and Medical Sciences, Qassim University, Unaizah, Department of Family and Community Medicine Department (Mohamed), King Khalid University Hospital, King Abdullah bin Abdul-Aziz University Hospital (Saeedi), Princess Nora bint Abdulrahman University, King Fahad Medical City (Al Jumah), Ministry of Health, King Abdullah International Medical Research Center-King Saud bin Abdulaziz University for Health Sciences (Al Jumah), Riyadh, and from King Fahad General Hospital (Alotaibi), Ministry of Health, Jedda, Kingdom of Saudi Arabia.
Jameelah A SaeediFrom the Department of Family and Community Medicine (Al-Wutayd), Unaizah College of Medicine and Medical Sciences, Qassim University, Unaizah, Department of Family and Community Medicine Department (Mohamed), King Khalid University Hospital, King Abdullah bin Abdul-Aziz University Hospital (Saeedi), Princess Nora bint Abdulrahman University, King Fahad Medical City (Al Jumah), Ministry of Health, King Abdullah International Medical Research Center-King Saud bin Abdulaziz University for Health Sciences (Al Jumah), Riyadh, and from King Fahad General Hospital (Alotaibi), Ministry of Health, Jedda, Kingdom of Saudi Arabia.
Hessa S AlotaibiFrom the Department of Family and Community Medicine (Al-Wutayd), Unaizah College of Medicine and Medical Sciences, Qassim University, Unaizah, Department of Family and Community Medicine Department (Mohamed), King Khalid University Hospital, King Abdullah bin Abdul-Aziz University Hospital (Saeedi), Princess Nora bint Abdulrahman University, King Fahad Medical City (Al Jumah), Ministry of Health, King Abdullah International Medical Research Center-King Saud bin Abdulaziz University for Health Sciences (Al Jumah), Riyadh, and from King Fahad General Hospital (Alotaibi), Ministry of Health, Jedda, Kingdom of Saudi Arabia.
Mohammed A Al JumahFrom the Department of Family and Community Medicine (Al-Wutayd), Unaizah College of Medicine and Medical Sciences, Qassim University, Unaizah, Department of Family and Community Medicine Department (Mohamed), King Khalid University Hospital, King Abdullah bin Abdul-Aziz University Hospital (Saeedi), Princess Nora bint Abdulrahman University, King Fahad Medical City (Al Jumah), Ministry of Health, King Abdullah International Medical Research Center-King Saud bin Abdulaziz University for Health Sciences (Al Jumah), Riyadh, and from King Fahad General Hospital (Alotaibi), Ministry of Health, Jedda, Kingdom of Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine whether body size in different age periods is associated with an increased risk of MS in Saudi Arabia.

methodsThis study included 307 MS patients and 307 healthy controls from clinics and hospital wards in three cities (Riyadh, Jeddah, and Dammam) in Saudi Arabia (2016-2017). We used Stunkard's standard body silhouettes to determine the participants' body sizes (from 1 to 9) during different age periods (school levels). We calculated adjusted odds ratios (AORs) and 95% confidence intervals (CIs) and performed multivariable analysis adjusted for age and gender.

resultsLarge body sizes (silhouettes 6-9) and body size 5 during intermediate school were associated with an increased risk of MS (AOR: 3.75, 95% CI: 1.10-12.78 and AOR: 3.75, 95% CI: 1.41-10, respectively). The smallest body size (1) during intermediate school was associated with a lower risk of MS (AOR: 0.39, 95% CI: 0.17-0.90) compared to body size 3.

conclusionOverweight and obesity during the intermediate school period (ages 13-15 years) are associated with an increased risk of MS, particularly among females.

Indexed as

Multiple SclerosisAdolescentCase-Control StudiesCross-Sectional StudiesFemaleHumansMaleObesityRisk FactorsSaudi Arabia

Identifiers

PMID35477920
PMCPMC9257916

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.