Evidence map›Paper›PMID 35477835›Full record

ArticleTrials2022

Clinical trial management: a profession in crisis?

E J Mitchell, K Goodman, N Wakefield, C Cochran, S Cockayne, S Connolly, R Desai, S Hartley, S A Lawton, K Oatey and 5 more

Abstract readLetter
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. What PIs want when hiring a clinical research coordinator.Journal of clinical and translational science · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

E J MitchellNottingham Clinical Trials Unit, School of Medicine, University of Nottingham, University Park, Nottingham, NG7 2RD, UK. eleanor.mitchell@nottingham.ac.uk.ORCID http://orcid.org/0000-0002-6998-4533
K GoodmanNMAHP Research Unit, Glasgow Caledonian University, Glasgow, G4 0NA, UK.
N WakefieldNottingham Clinical Trials Unit, School of Medicine, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
C CochranCentre for Healthcare and Randomised Controlled Trials (CHaRT), Health Services Research Unit, University of Aberdeen, Aberdeen, AB23 2ZD, UK.
S CockayneYork Trials Unit, Department of Health Sciences, University of York, York, YO10 5DD, UK.
S ConnollyRoyal Marsden Clinical Trials Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.
R DesaiKing's Ophthalmology Research Unit, King's College Hospital, London, SE5 9RS, UK.
S HartleyClinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, LS2 9JT, UK.
S A LawtonKeele Clinical Trials Unit, School of Medicine, Keele University, Keele, ST5 5BG, UK.
K OateyEdinburgh Clinical Trials Unit, University of Edinburgh, Edinburgh, EH16 4UX, UK.
S RhodesExeter Clinical Trials Unit, University of Exeter, St Luke's Campus, Exeter, EX1 2LU, UK.
J S SavageCancer Research UK Clinical Trials Unit, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
J TaylorBristol Randomised Trials Collaboration, Bristol Trials Centre, University of Bristol, 39 Whatley Road, Bristol, BS8 2PS, UK.
N F J YoussoufClinical Research Department, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
UK Trial Managers’ Network

Funding

Cancer Research UK 25354
6 · The paper itself

Abstract

Clinical trial managers play a vital role in the design and conduct of clinical trials in the UK. There is a current recruitment and retention crisis for this specialist role due to a complex set of factors, most likely to have come to a head due to the COVID-19 pandemic. Academic clinical trial units and departments are struggling to recruit trial managers to vacant positions, and multiple influences are affecting the retention of this highly skilled workforce. Without tackling this issue, we face major challenges in the delivery on the Department of Health and Social Care's Future of UK Clinical Research Delivery implementation plan. This article, led by a leading network of and for UK Trial Managers, presents some of the issues and ways in which national stakeholders may be able to address this.

Indexed as

Clinical Trials as TopicWorkforceCOVID-19HumansPandemicsResearch Design

Identifiers

PMID35477835
PMCPMC9044377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.