Evidence map›Paper›PMID 35477761›Full record

ArticleNature2022

Reversible RNA phosphorylation stabilizes tRNA for cellular thermotolerance.

Takayuki Ohira, Keiichi Minowa, Kei Sugiyama, Seisuke Yamashita, Yuriko Sakaguchi, Kenjyo Miyauchi, Ryo Noguchi, Akira Kaneko, Izumi Orita, Toshiaki Fukui and 2 more

Abstract read
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. tRNA modifications in viral replication.The Journal of biological chemistry · 2026
    Review
  6. Article
  7. RNA modifications in cancer and their detection: a review.Japanese journal of clinical oncology · 2026
    Review
  8. Article
  9. Article
  10. Archaeal RNA processing and regulation: expanding the functional landscape.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Crystal structures of free-state tRNARNA (New York, N.Y.) · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Takayuki Ohira *Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan. ohira_t@chembio.t.u-tokyo.ac.jp.ORCID http://orcid.org/0000-0002-1487-1312
Keiichi Minowa *Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan.
Kei SugiyamaDepartment of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan.
Seisuke YamashitaDepartment of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan.ORCID http://orcid.org/0000-0002-6970-8758
Yuriko SakaguchiDepartment of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan.
Kenjyo MiyauchiDepartment of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0002-4075-7660
Ryo NoguchiDepartment of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan.
Akira KanekoSchool of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
Izumi OritaSchool of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
Toshiaki FukuiSchool of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
Kozo TomitaDepartment of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan. kozo-tomita@edu.k.u-tokyo.ac.jp.ORCID http://orcid.org/0000-0002-7374-3898
Tsutomu SuzukiDepartment of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan. ts@chembio.t.u-tokyo.ac.jp.ORCID http://orcid.org/0000-0002-9731-1731

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-transcriptional modifications have critical roles in tRNA stability and function

Indexed as

ArchaeaRNA, TransferThermotoleranceExtreme EnvironmentsPhosphorylationRNA, ArchaealRNA Processing, Post-TranscriptionalUridineRNA, ArchaealRNA, TransferUridine

Identifiers

PMID35477761
PMCPMC9095486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.