Evidence map›Paper›PMID 35477357›Full record

ArticleBMC pulmonary medicine2022

Mixed-dust pneumoconiosis in a dental technician: a multidisciplinary diagnosis case report.

Luigi Di Lorenzo, Francesco Inchingolo, Antonella Pipoli, Filippo Cassano, Maria Elena Maggiore, Angelo Michele Inchingolo, Sabino Ceci, Assunta Patano, Giuseppina Malcangi, Antonio Mancini and 10 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC pulmonary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 1 country.

Luigi Di Lorenzo *Department of Interdisciplinary Medicine, University of Medicine Aldo Moro, 70124, Bari, Italy. luigi.dilorenzo@uniba.it.
Francesco Inchingolo *Department of Interdisciplinary Medicine, University of Medicine Aldo Moro, 70124, Bari, Italy. francecso.inchingolo@uniba.it.
Antonella Pipoli *Department of Interdisciplinary Medicine, University of Medicine Aldo Moro, 70124, Bari, Italy.
Filippo CassanoDepartment of Interdisciplinary Medicine, University of Medicine Aldo Moro, 70124, Bari, Italy.
Maria Elena MaggioreDepartment of Interdisciplinary Medicine, University of Medicine Aldo Moro, 70124, Bari, Italy.
Angelo Michele InchingoloDepartment of Interdisciplinary Medicine, University of Medicine Aldo Moro, 70124, Bari, Italy.
Sabino CeciDepartment of Interdisciplinary Medicine, University of Medicine Aldo Moro, 70124, Bari, Italy.
Assunta PatanoDepartment of Interdisciplinary Medicine, University of Medicine Aldo Moro, 70124, Bari, Italy.
Giuseppina MalcangiDepartment of Interdisciplinary Medicine, University of Medicine Aldo Moro, 70124, Bari, Italy.
Antonio ManciniDepartment of Interdisciplinary Medicine, University of Medicine Aldo Moro, 70124, Bari, Italy.
Giosi LongoNational Institute for Insurance Against Injuries at Work (INAIL), Bari, Italy.
Rossella AttimonelliNational Institute for Insurance Against Injuries at Work (INAIL), Bari, Italy.
Eugenio MaioranoDepartment of Emergency and Transplantation, Pathology Section, University of Bari, Bari, Italy.
Rocco LavianoDepartment of Earth and Geoenvironmental Sciences, University of Bari, Bari, Italy.
Nicola Mariano ManghisiDepartment of Prevention, Prevention and Safety at Work Service, Local Health Board of Brindisi, Brindisi, Italy.
Antonio ScaranoDepartment of Innovative Technologies in Medicine and Dentistry, University of Chieti-Pescara, 66100, Chieti, Italy. ascarano@unich.it.ORCID http://orcid.org/0000-0003-1374-6146
Felice LorussoDepartment of Innovative Technologies in Medicine and Dentistry, University of Chieti-Pescara, 66100, Chieti, Italy. drlorussofelice@gmail.com.
Antonio Di Lorenzo *Department of Biomedical Science and Human Oncology, University of Bari, 70124, Bari, Italy.
Alessio Danilo Inchingolo *Department of Interdisciplinary Medicine, University of Medicine Aldo Moro, 70124, Bari, Italy.
Gianna Dipalma *Department of Interdisciplinary Medicine, University of Medicine Aldo Moro, 70124, Bari, Italy.
University of Bari Aldo Moro · ITIstituto Nazionale per l'Assicurazione Contro gli Infortuni sul Lavoro · ITUniversity of Chieti-Pescara · ITOspedale A. Perrino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn dental laboratories, exposure to crystalline silica can occur during procedures that generate suspended mineral dusts, e.g. dispersion of mixing powders, removal of castings from molds grinding, polishing of castings and porcelain, and use of silica sand for blasting. There is also a large list of toxic agents (acrylic resins, polymeric materials, etc.) used to produce removable and fixed prostheses, but also impression materials and more. Using personal protective equipment and other aids reduces the exposure to these potentially harmful agents. CASE PRESENTATION: We report the case of a 42-year-old male dental technician who began to suffer from a dry cough and exertional dyspnea after approximately 15 years of work. The operations he conducted for his job resulted in the generation of crystalline silica, aluminum, chromium and titanium dust. The worker did not regularly wear personal protective equipment and some of the above operations were not carried out in closed circuit systems. The Chest X-ray showed diffused micronodules in the pulmonary interstitium of the upper-middle lobes, bilaterally, and a modest left basal pleural effusion. Simple spirometry showed small airway obstruction in its initial stage. High Resolution Computerized Tomography of the chest showed bilateral micronodulation of a miliariform type, with greater profusion to the upper lobes, also present in the visceral pleura, bilaterally. Histological examination showed aggregates of pigment-laden macrophages forming perivascular macules or arranged in a radial pattern around a core of sclerohyalinosis. Scanning Electron Microscopy and Energy Dispersive Spectrometry revealed several mineral particles, typically characterized by the presence of crystalline silica and metal aggregates. The environmental concentrations of total dust and its respirable fraction were all lower than the relative TLV-TWA-ACGIH, yet not negligible.

conclusionsThe above findings and a multidisciplinary assessment led to the diagnosis of mixed dust pneumoconiosis s/q with 2/2 profusion of occupational origin. This diagnosis in a dental technician was supported for the first time in literature by environmental exposure analysis.

Indexed as

DustPneumoconiosisAdultDental TechniciansHumansMaleMineralsSilicon DioxideDustMineralsSilicon DioxideDental technicianEnvironmental analysisHistologic analysisMineralogical analysisPneumoconiosis

Identifiers

PMID35477357
PMCPMC9044673
OpenAlexW4224942174

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.