Evidence map›Paper›PMID 35476990›Full record

ArticleCell reports2022

Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer.

Sohail Jahid, Jose A Ortega, Linh M Vuong, Isabella Maria Acquistapace, Stephanie J Hachey, Jessica L Flesher, Maria Antonietta La Serra, Nicoletta Brindani, Giuseppina La Sala, Jacopo Manigrasso and 12 more

Abstract readPublished Erratum
In one paragraph

Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Sohail Jahid
Jose A Ortega
Linh M Vuong
Isabella Maria Acquistapace
Stephanie J Hachey
Jessica L Flesher
Maria Antonietta La Serra
Nicoletta Brindani
Giuseppina La Sala
Jacopo Manigrasso
Jose M Arencibia
Sine Mandrup Bertozzi
Maria Summa
Rosalia Bertorelli
Andrea Armirotti
Rongsheng Jin
Zheng Liu
Chi-Fen Chen
Robert Edwards
Christopher C W Hughes
Marco De Vivo
Anand K Ganesan

Funding

CARCINOGENESIST32CA009054 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI EDINGER, AIMEE L, FRUMAN, DAVID ALEXANDER · 1985 to 2025
$8.6M
UCI P30 Skin Center Systems Biology CoreP30AR075047 · NIAMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI ANDERSEN, BOGI, GANESAN, ANAND K · 2019 to 2025
$5.1M
Identifying Therapeutic Targets for Stage III MelanomaR01CA244571 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI GANESAN, ANAND K · 2020 to 2024
$2.4M
Uncovering the Origin and Growth Regulation of Melanocytic NeviR56AR074641 · NIAMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI GANESAN, ANAND K · 2019 to 2019
$478k
NCI NIH HHS R01 CA244571NCI NIH HHS T32 CA009054NIAMS NIH HHS P30 AR075047NIAMS NIH HHS R56 AR074641
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID35476990
PMCPMC9128537

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.