ArticleCell reports2022
Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
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Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30citing papers in PubMed
6.5field-weighted citation impact, top 2% of its field
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Who cites it
30 citing papers in PubMed, 54 citations in OpenAlex.
- Importance of Recognizing Renal Tubular Disorders as a Cause of Bone Hypomineralization and Fractures in Adults.Diagnostics (Basel, Switzerland) · 2026Review
- Immunohistochemical Analysis of pH-Sensitive TRPV5 in Common Skin Tumors.International journal of molecular sciences · 2026Article
- Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin.The Journal of physiology · 2026Review
- Molecular mechanism of menthol-induced TRPV5 channel inhibition.Nature communications · 2026Article
- Structural landscape of activation, desensitization and inhibition in the human TRPM4 channel.Nature structural & molecular biology · 2026Article
- A novel small molecule NJH-13 induces pyroptosis via the CaJournal of advanced research · 2025Article
- Physiological functions and pharmacological targeting of transient receptor potential channels.Pharmacological reviews · 2025Review
- Article
- Mechanosensing of Shear Stress and Uterine Spiral Artery Remodeling by Invasive Trophoblasts in Early Pregnancy.International journal of molecular sciences · 2025Review
- Forty sites of TRP channel regulation.Current opinion in chemical biology · 2025Review
- Advances in the Study for Modulators of Transient Receptor Potential Vanilloid (TRPV) Channel Family.Current topics in medicinal chemistry · 2025Review
- Unlocking the potential of cardiac TRP channels using knockout mice models.Frontiers in physiology · 2025Article
- The role of transient receptor potential channels in chronic kidney disease-mineral and bone disorder.Frontiers in pharmacology · 2025Review
- Calmodulin regulates TRPV5 intracellular trafficking and plasma membrane abundance.The Journal of physiology · 2024Article
- Structural basis of TRPV1 inhibition by SAF312 and cholesterol.Nature communications · 2024Article
- Calcium signalling and transport in the kidney.Nature reviews. Nephrology · 2024Review
- Dynamic molecular portraits of ion-conducting pores characterize functional states of TRPV channels.Communications chemistry · 2024Article
- The Rise in Tubular pH during Hypercalciuria Exacerbates Calcium Stone Formation.International journal of molecular sciences · 2024Article
- Molecular details of ruthenium red pore block in TRPV channels.EMBO reports · 2024Article
- Structural mechanism of TRPV5 inhibition by econazole.Structure (London, England : 1993) · 2024Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Edwin C FluckDepartment of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Biochemistry and Molecular Biophysics Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Aysenur Torun YaziciDepartment of Pharmacology, Physiology and Neuroscience, New Jersey Medical School, Rutgers University, Newark, NJ 07103, USA.
Tibor RohacsDepartment of Pharmacology, Physiology and Neuroscience, New Jersey Medical School, Rutgers University, Newark, NJ 07103, USA.
Vera Y Moiseenkova-BellDepartment of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: vmb@pennmedicine.upenn.edu.
Rutgers, The State University of New Jersey · USTranslational Therapeutics (United States) · US
Funding
Regulation of the Intestinal Ca2+ Channels TRPV6R01GM093290 · NIGMS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI CARNEVALE, VINCENZO, ROHACS, TIBOR · 2011 to 2025
$4.9MStructure and Function of TRPV channelsR35GM144120 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Vera Moiseenkova-Bell · 2022 to 2026
$4.2MStructural biology and molecular biophysics training programT32GM132039 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Ben E. Black, Elizabeth Rhoades · 2019 to 2026
$3.3MStructural Insights into TRPV Channel GatingR01GM103899 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI MOISEENKOVA-BELL, VERA · 2013 to 2021
$3.2MWest/Midwest Consortium for High-Resolution Cryo Electron MicroscopyU24GM116792 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AGBANDJE-MCKENNA, MAVIS, DOKLAND, TERJE · 2016 to 2020
$3.0MMolecular mechanisms of TRPV5 gatingR01GM129357 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI MOISEENKOVA-BELL, VERA · 2018 to 2021
$1.7MHIGH-END CRYOEM INSTRUMENT FOR UCLA ELECTRON IMAGING CTR FOR NANOMACHINES: AIDSS10RR023057 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2006 to 2006
$1.6MDirect Detection Device for atomic resolution cryoEM of macromolecular complexesS10OD018111 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2014 to 2014
$598kComputational Resource for Structural Biology and Molecular BiophysicsS10OD023592 · OD · UNIVERSITY OF PENNSYLVANIA · PI SHARP, KIM A · 2017 to 2017
$402kNCRR NIH HHS S10 RR023057NIGMS NIH HHS R01 GM093290NIGMS NIH HHS R01 GM103899NIGMS NIH HHS R01 GM129357NIGMS NIH HHS R35 GM144120NIGMS NIH HHS T32 GM132039NIGMS NIH HHS U24 GM116792NIH HHS S10 OD018111NIH HHS S10 OD023592
Abstract
Transient receptor potential vanilloid 5 (TRPV5) is a kidney-specific Ca
Indexed as
CalciumTRPV Cation ChannelsCalcium SignalingCalmodulinCryoelectron MicroscopyCyclic AMP-Dependent Protein KinasesParathyroid HormoneCalciumCalmodulinCyclic AMP-Dependent Protein KinasesParathyroid HormoneTRPV Cation ChannelscalmodulinCaMCP: Molecular biologyCP: Neurosciencecryoelectron microscopycryo-EMpHPI(4,5)P(2)PKAprotein kinase Atransient receptor potential channelTRP channel
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.