ArticlePloS one2022
Impact of oxytetracycline exposure on the digestive system microbiota of Daphnia magna.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Protective effects of Quercus brantii fruit extract against oxytetracycline-induced intestinal injury in zebrafish larvae.Fish physiology and biochemistry · 2026Article
- From Gut to Brain: Glyphosate and Triclosan Impair Microbiome Composition, Neuroactive Metabolites, and Cognitive and Ecological Fitness inEnvironmental science & technology · 2026Article
- TiFrontiers in microbiology · 2026Article
- Lactobacillus rhamnosus and Staphylococcus epidermidis in gut microbiota: in vitro antimicrobial resistance.AMB Express · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antibiotics are used to treat serious illness, but may also be used extraneously or as a preventative measure in many farm animals. This usage increases the potential for unintentional exposure to a variety of organisms. When antibiotics enter aquatic environments, Daphnia magna are especially vulnerable as they filter-feed in freshwater environments. Oxytetracycline (OTC) is a commonly-used broad-spectrum antibiotic used to treat a variety of mammalian diseases. In this study, the impact of OTC on D. magna mortality and gut biota were studied using both cultivation and sequencing-based approaches. Mortality rates were extremely low with the LD50 >2,000ppm. However, OTC impacted abundance and species diversity of intestinal microorganisms in the gut of the D. magna in abundance as well as species diversity. In control organisms, Pseudomonas putida and Aeromonas hydrophila were both present while only P. putida was found in OTC-exposed organisms. Disruption of the intestinal biota in D. magna could have implications on long-term survival, energy expenditure, and reproduction.
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Registered trials
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