Evidence map›Paper›PMID 35476258›Full record

ArticleCanadian journal of public health = Revue canadienne de sante publique2022

COVID-19 vaccine uptake and intention during pregnancy in Canada.

Laura Reifferscheid, Emmanuel Marfo, Ali Assi, Eve Dubé, Noni E MacDonald, Samantha B Meyer, Julie A Bettinger, S Michelle Driedger, Joan Robinson, Manish Sadarangani and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Canadian journal of public health = Revue canadienne de sante publique, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  6. Pandemic Pregnancy Experiences and Risk Mitigation Behaviors: COVID-19 Vaccination Uptake in Canada.International journal of environmental research and public health · 2025
    Article
  7. Article
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  11. Impact of Covid-19 on risk of severe maternal morbidity.Critical care (London, England) · 2023
    Article
  12. Article
  13. Article
  14. Coronavirus Disease-2019 Vaccine Hesitancy.Pediatric clinics of North America · 2023
    Review
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 1 country.

Laura ReifferscheidFaculty of Nursing, University of Alberta, Edmonton, AB, Canada.
Emmanuel MarfoFaculty of Nursing, University of Alberta, Edmonton, AB, Canada.
Ali AssiFaculty of Nursing, University of Alberta, Edmonton, AB, Canada.
Eve DubéInstitut national de santé publique du Québec, Québec City, QC, Canada.
Noni E MacDonaldDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.
Samantha B MeyerSchool of Public Health Sciences, University of Waterloo, Waterloo, ON, Canada.
Julie A BettingerVaccine Evaluation Centre, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
S Michelle DriedgerDepartment of Community Health Sciences, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Joan RobinsonDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Manish SadaranganiVaccine Evaluation Centre, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Sarah E WilsonICES, Toronto, ON, Canada.
Karen BenziesFaculty of Nursing, University of Calgary, Calgary, AB, Canada.
Samuel Lemaire-PaquetteCentre de Recherche du CHUS, Sherbrooke, QC, Canada.
Arnaud GagneurCentre de Recherche du CHUS, Sherbrooke, QC, Canada.
Shannon E MacDonaldFaculty of Nursing, University of Alberta, Edmonton, AB, Canada. smacdon@ualberta.ca.ORCID 0000-0003-4675-4433
University of Alberta · CAUniversity of British Columbia · CACentre Hospitalier Universitaire de Sherbrooke · CADalhousie University · CAInstitut National de Santé Publique du Québec · CAUniversité de Sherbrooke · CAUniversity of Calgary · CAUniversity of Manitoba · CAUniversity of Toronto · CAUniversity of Waterloo · CA

Funding

CIHR
6 · The paper itself

Abstract

objectiveTo investigate COVID-19 vaccine uptake and intent among pregnant people in Canada, and determine associated factors.

methodsWe conducted a national cross-sectional survey among pregnant people from May 28 through June 7, 2021 (n = 193). Respondents completed a questionnaire to determine COVID-19 vaccine acceptance (defined as either received or intend to receive a COVID-19 vaccine during pregnancy), factors associated with vaccine acceptance, and rationale for accepting/not accepting the vaccine.

resultsOf 193 respondents, 57.5% (n = 111) reported COVID-19 vaccine acceptance. Among those who did not accept the vaccine, concern over vaccine safety was the most commonly cited reason (90.1%, n = 73), and 81.7% (n = 67) disagreed with receiving a vaccine that had not been tested in pregnant people. Confidence in COVID-19 vaccine safety (aOR 16.72, 95% CI: 7.22, 42.39), Indigenous self-identification (aOR 11.59, 95% CI: 1.77, 117.18), and employment in an occupation at high risk for COVID-19 exposure excluding healthcare (aOR 4.76, 95% CI: 1.32, 18.60) were associated with vaccine acceptance. Perceived personal risk of COVID-19 disease was not associated with vaccine acceptance in the multivariate model.

conclusionVaccine safety is a primary concern for this population. Safety information should be communicated to this population as it emerges, along with clear messaging on the benefits of vaccination, as disease risk is either poorly understood or poorly valued in this population.

Indexed as

COVID-19VaccinesCanadaCOVID-19 VaccinesCross-Sectional StudiesFemaleHumansIntentionPatient Acceptance of Health CarePregnancyVaccinationCOVID-19 VaccinesVaccinesCOVID-19ImmunizationIntentionPandemicPregnancyUptakeVaccination

Identifiers

PMID35476258
PMCPMC9045023
OpenAlexW4224924189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.