Evidence map›Paper›PMID 35476189›Full record

ArticleApplied biochemistry and biotechnology2022

Comparative Analysis of In Vitro Enzyme Inhibitory Activities and Phytochemicals from Platycladus orientalis (L.) Franco via Solvent Partitioning Method.

Keat Lam Ho, Zhi Xiang Ng, Chee Woon Wang, Sarni Mat Junit, Siew Huah Lim, Chek Tung Ngo, Audrey Chee Hui Yong, Phaik Har Yong

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In one paragraph

Article in Applied biochemistry and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Ethyl acetate extract fromFrontiers in pharmacology · 2026
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  3. Neuroprotective effects ofFrontiers in molecular biosciences · 2026
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  4. Effects ofAnimals : an open access journal from MDPI · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Keat Lam HoSchool of Biosciences, Faculty of Science and Engineering, University of Nottingham Malaysia, Semenyih, Selangor, Malaysia.
Zhi Xiang NgSchool of Biosciences, Faculty of Science and Engineering, University of Nottingham Malaysia, Semenyih, Selangor, Malaysia.
Chee Woon WangDepartment of Biochemistry, Faculty of Medicine, Bioscience and Nursing, MAHSA University, Jenjarom, Selangor, Malaysia.
Sarni Mat JunitDepartment of Molecular Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Siew Huah LimDepartment of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia.
Chek Tung NgoOptimax Sunway Eye Specialist Centre, Bandar Sunway, Selangor, Malaysia.
Audrey Chee Hui YongDepartment of Medicinal Chemistry, Faculty of Pharmacy, MAHSA University, Selangor, Jenjarom, Malaysia.
Phaik Har YongSchool of Bioscience, Faculty of Medicine, Bioscience and Nursing, MAHSA University, Jenjarom, Selangor, Malaysia. yphaikhar@gmail.com.ORCID http://orcid.org/0000-0002-5888-9856
Mahsa University · MYUniversity of Malaya · MYUniversity of Nottingham Malaysia Campus · MYSunway University · MY

Funding

Malaysian Allied Health Sciences Academy RP157-05-19Ministry of Higher Education Malaysia FRGS/1/2020/SKK06/MAHSA/03/1
6 · The paper itself

Abstract

The extraction of plant bioactive compounds from Platycladus orientalis (L.) Franco remains a great challenge due to the different chemical groups. This study aimed to compare the bioactive compounds with enzyme inhibitory effect from P. orientalis via solvent partitioning method. Dried leaf samples were macerated and fractionated with six solvents of different polarities. The phenolic, flavonoid, tannin, saponin, alkaloid and pharmacological activities including anti-inflammatory, anti-diabetic, antioxidant and anti-glycation potential were compared across the six plant fractions. Toxicity assessment was performed with an in vivo brine shrimp model. The varying levels of bioactive compounds in ethyl acetate (phenolics, flavonoids), hexane (saponins, tannins) and chloroform (alkaloids) fractions clearly demonstrated the significant impact of solvent polarity on the extraction of bioactive compounds. The reducing potential (r = 0.67), IC

Indexed as

AntioxidantsSaponinsFlavonoidsPhenolsPhytochemicalsPlant ExtractsSolventsTanninsAntioxidantsFlavonoidsPhenolsPhytochemicalsPlant ExtractsSaponinsSolventsTanninsAnti-diabetesAnti-glycationAnti-inflammationChinese ThujaCytotoxicityPhenolic

Identifiers

PMID35476189
OpenAlexW4224984817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.