ArticleEuropean journal of clinical pharmacology2022
Why hospital-based healthcare professionals do not report adverse drug reactions: a mixed methods study using the Theoretical Domains Framework.
Article in European journal of clinical pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- When does Follow-up on Adverse Events Improve the Understanding of Medicine and Vaccine Safety? Insights from Global Expert Perspectives.Drug safety · 2026Article
- Knowledge, attitude, and practice of pharmacovigilance among healthcare professionals at a tertiary level hospital, Sudan: a cross sectional study.BMC health services research · 2025Article
- Trends in adverse drug reaction reporting in eight selected countries after the implementation of new pharmacovigilance regulation in 2012: a joinpoint regression analysis.European journal of clinical pharmacology · 2025Article
- Transformative education: Enhancing pharmacovigilance awareness among healthcare professionals through sensitization initiatives.Journal of family medicine and primary care · 2025Article
- Oropharyngeal Adverse Events to Drugs and Vaccines: Pharmacovigilance Data From Italy (2019-2021).Oral diseases · 2025Article
- Complex chronic adverse events following immunization: a systemic critique and reform proposal for vaccine pharmacovigilance.Therapeutic advances in drug safety · 2025Article
- Pharmacovigilance in Australia: how do adverse event reports from clinicians contribute to medicine and vaccine safety?Australian prescriber · 2024Review
- Pharmacovigilance Practices by Healthcare Providers in Oncology: A Cross-Sectional Study.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Causality assessment of adverse drug reaction: A narrative review to find the most exhaustive and easy-to-use tool in post-authorization settings.Journal of applied biomedicine · 2023Review
- Linking Activity Theory Within User-Centered Design: Novel Framework to Inform Design and Evaluation of Adverse Drug Reaction Reporting Systems in Pharmacy.JMIR human factors · 2023Article
- Sodium-glucose cotransporter-2 (SGLT2) inhibitors and the reporting of falls and fractures: an european pharmacovigilance analysis.Frontiers in pharmacology · 2023Article
- Barriers and Facilitators Influencing Real-time and Digital-Based Reporting of Adverse Drug Reactions by Community Pharmacists: Qualitative Study Using the Task-Technology Fit Framework.Interactive journal of medical research · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
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Abstract
purposeAdverse drug reaction (ADR) underreporting is highly prevalent across the world. This study aimed to identify factors associated with ADR reporting and map these to a behavioural change framework to help inform future interventions designed to improve ADR underreporting.
methodsA mixed methods survey was distributed to healthcare professionals at a tertiary hospital in Sydney, Australia. Quantitative data was analysed using logistic regression to identify factors that predict ADR reporting. Qualitative data was evaluated using content analysis. These were then integrated and mapped to the 14 domains within the Theoretical Domains Framework (TDF) to identify target areas relevant for improving ADR reporting.
resultsOne hundred thirty-three healthcare professionals completed the survey. Knowing how to report ADRs (OR 4.56, 95%CI 1.95-10.7), having been trained on ADR reporting (OR 2.72, 95%CI 1.29-5.77), and encountering ADRs as part of clinical practice (OR 10.3, 95%CI 3.59-29.4) were significant predictors of reporting an ADR. Content analysis identified three categories: modifying the ADR reporting process, enabling clinicians to report ADRs, and creating a positive ADR reporting culture. After data integration, the three target TDF domains were knowledge, environmental context/resources, and beliefs about consequences.
conclusionFuture interventions designed to improve ADR reporting should address these target domains to instigate behaviour change in healthcare professionals' reporting of ADRs.
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