Evidence map›Paper›PMID 35476118›Full record

ArticleOrthopadie (Heidelberg, Germany)2022

[Does inflammatory activity of Charcot foot affect successful corrective arthrodesis?]

Alexander T Mehlhorn, Ulrich Illgner, Stefan Lemperle, Verena Huber, Hubert Hoerterer, Oliver Gottschalk, Maria Anna Legrand, Veit Krenn, Markus Walther

Abstract read
PubMed Publisher
In one paragraph

Article in Orthopadie (Heidelberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Alexander T MehlhornZentrum für Fuß- und Sprunggelenkschirurgie, Schönklinik München-Harlaching, München, Deutschland. amehlhorn@schoen-klinik.de.
Ulrich IllgnerOrthopädische Privatpraxis Seintsch Illgner, Koblenz, Deutschland.
Stefan LemperleZentrum für Fuß- und Sprunggelenkschirurgie, Schönklinik München-Harlaching, München, Deutschland.
Verena HuberZentrum für Fuß- und Sprunggelenkschirurgie, Schönklinik München-Harlaching, München, Deutschland.
Hubert HoertererZentrum für Fuß- und Sprunggelenkschirurgie, Schönklinik München-Harlaching, München, Deutschland.
Oliver GottschalkZentrum für Fuß- und Sprunggelenkschirurgie, Schönklinik München-Harlaching, München, Deutschland.
Maria Anna LegrandZentrum für Anästhesiologie und Intensivmedizin, Schönklinik München-Harlaching, München, Deutschland.
Veit KrennMVZ-Zentrum für Histologie, Zytologie und Molekulare Diagnostik GmbH, Trier, Deutschland.
Markus WaltherZentrum für Fuß- und Sprunggelenkschirurgie, Schönklinik München-Harlaching, München, Deutschland.
Schön Klinik München Harlaching · DELudwig-Maximilians-Universität München · DEOrthopädische Praxis · DEZentrum für Pathologie und Zytodiagnostik · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeuro-osteoarthropathy of the foot (CN) is divided into an active and inactive stage, with impact on the further treatment. The histopathological Charcot score (HCS) can be used, to grade the inflammatory activity in tissue samples. RESEARCH QUESTION: This study aims to clarify whether successful bony healing after arthrodesis is related to inflammatory activity of the disease. MATERIAL AND

methodN = 80 patients underwent corrective arthrodesis of the midfoot (group 1) or hindfoot/ankle (group 2). A distinction was made between patients with/without diabetes mellitus and with/without pain perception. Intraoperative samples were taken to determine HCS. The osseous healing of the arthrodesis was determined by computed tomography 12 weeks postoperatively.

resultsThere was an indirect correlation between bony consolidation and HCS. In group 2, there was a significantly worse bony healing in patients without pain sensation. There seems to be a tendency for HCS to be increased in patients without diabetes/no pain sensation. DISCUSSION: The present study confirms the assumption that corrective arthrodesis should be performed in the inactive stage of CN only. High activity levels obviously impede bony healing. HCS represents a relevant prognostic tool for surgical treatment.

Indexed as

Arthropathy, NeurogenicDiabetic FootAnkle JointArthrodesisFootHumansArthrodesisArthropathy, neurogenicDiabetic footFoot deformities, acquiredPain perception

Identifiers

PMID35476118
OpenAlexW4224989733

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.