Evidence map›Paper›PMID 35476072›Full record

ReviewBiomaterials science2022

Nanoparticle personalized biomolecular corona: implications of pre-existing conditions for immunomodulation and cancer.

Jacob Shaw, Ryan M Pearson

Abstract readReview
In one paragraph

Review in Biomaterials science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Lipid nanoparticles fromMolecular therapy. Methods & clinical development · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jacob ShawDepartment of Microbiology and Immunology, University of Maryland School of Medicine, 685 W. Baltimore Street, Baltimore, MD 21201, USA. rpearson@rx.umaryland.edu.ORCID http://orcid.org/0000-0002-5885-1006
Ryan M PearsonDepartment of Microbiology and Immunology, University of Maryland School of Medicine, 685 W. Baltimore Street, Baltimore, MD 21201, USA. rpearson@rx.umaryland.edu.ORCID http://orcid.org/0000-0002-7857-0973

Funding

UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTERSUPPORT GRANTP30CA134274 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI Vu H. Duong · 2008 to 2026
$51.0M
Polymeric nanoassemblies for precise tuning of immune responses (Supplement for Equipment Purchase)R35GM142752 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI PEARSON, RYAN MATTHEW · 2021 to 2025
$2.1M
NCI NIH HHS P30 CA134274NIGMS NIH HHS R35 GM142752
6 · The paper itself

Abstract

Nanoparticles (NPs) have demonstrated great promise as immunotherapies for applications ranging from cancer, autoimmunity, and infectious disease. Upon encountering biological fluids, NPs rapidly adsorb biomolecules, forming the "biomolecular corona" (BC), and the altered character of NPs due to their newly acquired biological identity can impact their

Indexed as

NanoparticlesNeoplasmsProtein CoronaHumansImmunomodulationPreexisting Condition CoverageTissue DistributionProtein Corona

Identifiers

PMID35476072
PMCPMC9117514

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.