ArticleHuman vaccines & immunotherapeutics2022
Disease burden in patients with severe hand, foot, and mouth disease in Jiangsu Province: a cross-sectional study.
Article in Human vaccines & immunotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 22 citations in OpenAlex.
- The epidemiology and disease burden of enterovirus infections among hospitalized children in China: An 8-year national cross-sectional study.Virologica Sinica · 2026Article
- Epidemiological characteristics and influencing factors of hand, foot and mouth disease reinfection cases in a large district of southern China.Frontiers in public health · 2026Article
- Economic evaluation of including the EV71 vaccine in the national immunization program: a modeling study in Guangxi, China.Frontiers in public health · 2026Article
- Spatiotemporal Distribution of Hand, Foot, and Mouth Disease and the Influence of Air Pollutants and Socioeconomic Factors on Incidence in Fujian, China.Tropical medicine and infectious disease · 2025Article
- Epidemiological trends of hand, foot, and mouth disease in children under age 10, Jiangning District, Jiangsu, China (2009-2023).BMC infectious diseases · 2025Article
- A serosurvey study of hand, foot and mouth disease in healthy children aged 6 to 71 months old in West Bandung and Bandung Region, Indonesia.BMC infectious diseases · 2025Observational
- Article
- Epidemiological characteristics and influencing factors of hand, foot and mouth disease reinfection cases in Jiulongpo District, Chongqing, China, 2009-2023.Frontiers in public health · 2025Article
- Influence of the Enterovirus 71 Vaccine and the COVID-19 Pandemic on Hand, Foot, and Mouth Disease in China Based on Counterfactual Models: Observational Study.JMIR public health and surveillance · 2024Observational
- Article
- A screening study on the detection strain of Coxsackievirus A6: the key to evaluating neutralizing antibodies in vaccines.Emerging microbes & infections · 2024Article
- Impact of non-pharmacological interventions on incidence of hand, foot and mouth disease during the COVID-19 pandemic: a large population-based observational study.BMC infectious diseases · 2024Observational
- Health-Related Quality of Life and Economic Burden Among Hospitalized Children with Hand, Foot, and Mouth Disease: A Multiregional Study in China.PharmacoEconomics - open · 2024Article
- A hybrid model for hand-foot-mouth disease prediction based on ARIMA-EEMD-LSTM.BMC infectious diseases · 2023Article
- Research on hand, foot and mouth disease incidence forecasting using hybrid model in mainland China.BMC public health · 2023Article
- Impact of meteorological factors on the incidence of hand-foot-mouth disease in Yangzhou from 2017 to 2022: a time series study.Frontiers in public health · 2023Article
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to estimate the disease burden and health-related quality of life (HRQOL) among patients with severe hand, foot, and mouth disease (HFMD) in Jiangsu Province, China. We analyzed the surveillance data of HFMD cases in Jiangsu Province from 2009 to 2020. Moreover, a cross-sectional study was conducted in Nanjing and Suzhou, China, between January 2017 and May 2018. Patients with severe HFMD and their parents were recruited from selected hospitals. Questionnaires and hospital management systems were used to collect data on direct economic burden. The HRQOL of children was assessed using the TNO-AZL Preschool Quality of Life (TAPQOL) scale. A total of 1,348,737 confirmed cases of HFMD were reported to the NNDRS in Jiangsu province during 2009-2020. Of these, 9,622 were severe cases, with 62 (.64%) of these being fatal. From January 2017 to May 2018, data was collected from 362 severe HFMD cases using a structured questionnaire. The median per capita direct economic burden was RMB 16142.88, and was associated with the region and length of hospital stay (
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