Trial reportCognitive behaviour therapy2022
A SMART approach to personalized care: preliminary data on how to select and sequence skills in transdiagnostic CBT.
Trial report in Cognitive behaviour therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06722781 (UpLift-X Trial 1), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
UpLift-X Trial 1: A Cluster Factorial Randomised Controlled Trial of Digitally-enabled Group Psychotherapy for Common Mental Disorders
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Inclusion of People of Color in Randomized Controlled Trials for the Unified Protocol: A Systematic Review.Journal of racial and ethnic health disparities · 2026Pooled it
- Next-Generation Cognitive-Behavioral Therapy for Depression: Integrating Digital Tools, Teletherapy, and Personalization for Enhanced Mental Health Outcomes.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Evaluation of a transdiagnostic mental health intervention in German primary care: a parallel-group, two-arm, cluster randomised controlled pilot study.BMC primary care · 2026Trial
- Symptom Trajectories in Patients With Anxiety Disorders During Transdiagnostic Cognitive Behavioral Therapy.Depression and anxiety · 2026Trial
- Prescriptive Predictors of Mindfulness Ecological Momentary Intervention for Social Anxiety Disorder: Machine Learning Analysis of Randomized Controlled Trial Data.JMIR mental health · 2025Trial
- Web-based interpretation bias training to reduce anxiety: A sequential, multiple-assignment randomized trial.Journal of consulting and clinical psychology · 2024Trial
- Assessing Theories of State and Trait Change in Neuroticism and Symptom Improvement in the Unified Protocol.Behavior therapy · 2024Trial
- The effects of the Unified Protocol and Unified Protocol skills on loneliness in the COVID-19 pandemic.Depression and anxiety · 2022Trial
- A Preliminary Evaluation of the Unified Protocol among Trauma-Exposed Adults with and without PTSD.International journal of environmental research and public health · 2021Trial
- [Modular psychotherapy-Toward personalized psychotherapy].Der Nervenarzt · 2026Review
- Evaluation of a transdiagnostic mental health intervention in German primary care: study protocol for a parallel-group, two-arm, cluster randomised controlled pilot study.Pilot and feasibility studies · 2025Article
- Which symptom to address in psychological treatment for cancer survivors when fear of cancer recurrence, depressive symptoms, and cancer-related fatigue co-occur? Exploring the level of agreement between three systematic approaches to select the focus of treatment.Journal of cancer survivorship : research and practice · 2024Article
- Using the 'Leapfrog' Design as a Simple Form of Adaptive Platform Trial to Develop, Test, and Implement Treatment Personalization Methods in Routine Practice.Administration and policy in mental health · 2024Article
- TONI - One for all? Participatory development of a transtheoretic and transdiagnostic online intervention for blended care.Internet interventions · 2024Article
- Skill Use Mediates the Within-Person Effect of the Alliance on Session-to-Session Changes in Anxiety and Depression in the Unified Protocol.Journal of mood and anxiety disorders · 2024Article
- Do Unified Protocol modules exert general or unique effects on anxiety, depression, and transdiagnostic targets?Journal of mood and anxiety disorders · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Given that over 20 million adults each year do not receive care for their mental health difficulties, it is imperative to improve system-level capacity issues by increasing treatment efficiency. The present study aimed to collect feasibility/acceptability data on two strategies for increasing the efficiency of cognitive behavioral therapy: (1) personalized skill sequences and (2) personalized skill selections. Participants (N = 70) with anxiety and depressive disorders were enrolled in a pilot sequential multiple assignment randomized trial (SMART). Patients were randomly assigned to receive skill modules from the Unified Protocol in one of three sequencing conditions: standard, sequences that prioritized patients' relative strengths, and sequences that prioritized relative deficits. Participants also underwent a second-stage randomization to either receive 6 sessions or 12 sessions of treatment. Participants were generally satisfied with the treatment they received, though significant differences favored the Capitalization and Full duration conditions. There were no differences in trajectories of improvement as a function of sequencing condition. There were also no differences in end-of-study outcomes between brief personalized treatment and full standard treatment. Thus, it may be feasible to deliver CBT for personalized durations, though this may not substantially impact trajectories of change in anxiety or depressive symptoms.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.