Evidence map›Paper›PMID 35475783›Full record

ArticleeLife2022

Mechanical stimulation promotes enthesis injury repair by mobilizing

Han Xiao, Tao Zhang, Changjun Li, Yong Cao, Linfeng Wang, Huabin Chen, Shengcan Li, Changbiao Guan, Jianzhong Hu, Di Chen and 2 more

Open access · greenAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  8. Mechanism by which mechanical stimulation regulates chondrocyte apoptosis and matrix metabolism via primary cilia to delay osteoarthritis progression.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Tendon mechanobiology in the context of tendon biofabrication.Frontiers in bioengineering and biotechnology · 2025
    Review
  13. Achieving tendon enthesis regeneration across length scales.Current opinion in biomedical engineering · 2024
    Article
  14. Article
  15. Article
  16. Interfacial Tissue Regeneration with Bone.Current osteoporosis reports · 2024
    Review
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Han XiaoDepartment of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.
Tao ZhangDepartment of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.
Changjun LiNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Yong CaoKey Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China.
Linfeng WangDepartment of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.
Huabin ChenDepartment of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.
Shengcan LiDepartment of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.
Changbiao GuanDepartment of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.
Jianzhong HuKey Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China.
Di ChenFaculty of Pharmaceutical Sciences, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Can ChenKey Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China.
Hongbin LuDepartment of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0001-7749-3593
Central South University · CNXiangya Hospital Central South University · CNSoil and Fertilizer Institute of Hunan Province · CNShenzhen Institutes of Advanced Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proper mechanical stimulation can improve rotator cuff enthesis injury repair. However, the underlying mechanism of mechanical stimulation promoting injury repair is still unknown. In this study, we found that

Indexed as

Rotator Cuff InjuriesTransforming Growth Factor beta1AnimalsMiceRotator CuffTransforming Growth Factor beta1enthesismechanical stimulationmouseprimary ciliaPrx1+ cellsregenerative medicinestem cellsTGF-β

Identifiers

PMID35475783
PMCPMC9094755
OpenAlexW4224982729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.