Evidence map›Paper›PMID 35475734›Full record

ArticlemSphere2022

A 265-Nanometer High-Power Deep-UV Light-Emitting Diode Rapidly Inactivates SARS-CoV-2 Aerosols.

Hiroshi Ueki, Mutsumi Ito, Yuri Furusawa, Seiya Yamayoshi, Shin-Ichiro Inoue, Yoshihiro Kawaoka

Abstract read
In one paragraph

Article in mSphere, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Effectiveness of Ultraviolet-C (UV-C) Irradiation on the Viability of AirborneInternational journal of environmental research and public health · 2022
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hiroshi UekiDepartment of Virology, Institute of Medical Science, University of Tokyogrid.26999.3d, Tokyo, Japan.
Mutsumi ItoDepartment of Virology, Institute of Medical Science, University of Tokyogrid.26999.3d, Tokyo, Japan.
Yuri FurusawaDepartment of Virology, Institute of Medical Science, University of Tokyogrid.26999.3d, Tokyo, Japan.
Seiya YamayoshiDepartment of Virology, Institute of Medical Science, University of Tokyogrid.26999.3d, Tokyo, Japan.ORCID 0000-0001-7768-5157
Shin-Ichiro InoueAdvanced ICT Research Institute, National Institute of Information and Communications Technology (NICT), Kobe, Japan.
Yoshihiro KawaokaDepartment of Virology, Institute of Medical Science, University of Tokyogrid.26999.3d, Tokyo, Japan.ORCID 0000-0001-5061-8296

Funding

NIAID NIH HHS HHSN272201400008C
6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (COVID-19) is an acute respiratory infection transmitted by droplets, aerosols, and contact. Controlling the spread of COVID-19 and developing effective decontamination options are urgent issues for the international community. Here, we report the quantitative inactivation of SARS-CoV-2 in liquid and aerosolized samples by a state-of-the-art, high-power, AlGaN-based, single-chip compact deep-UV (DUV) light-emitting diode (LED) that produces a record continuous-wave output power of 500 mW at its peak emission wavelength of 265 nm. Using this DUV-LED, we observed a greater-than-5-log reduction in infectious SARS-CoV-2 in liquid samples within very short irradiation times (<0.4 s). When we quantified the efficacy of the 265-nm DUV-LED in inactivating SARS-CoV-2, we found that DUV-LED inactivation of aerosolized SARS-CoV-2 was approximately nine times greater than that of SARS-CoV-2 suspension. Our data demonstrate that this newly developed, compact, high-power 265-nm DUV-LED irradiation system with remarkably high inactivation efficiency for aerosolized SARS-CoV-2 could be an effective and practical tool for controlling SARS-CoV-2 spread.

Indexed as

COVID-19SARS-CoV-2AerosolsHumansSuspensionsUltraviolet RaysAerosolsSuspensionsaerosolsCOVID-19deep UVLEDSARS-CoV-2

Identifiers

PMID35475734
PMCPMC9044969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.