Evidence map›Paper›PMID 35475642›Full record

ArticlemBio2022

Candida albicans Filamentation Does Not Require the cAMP-PKA Pathway

Rohan S Wakade, Juraj Kramara, Melanie Wellington, Damian J Krysan

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. International journal of molecular sciences · 2026
    Article
  7. ThemBio · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Temporal dynamics ofmSphere · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. bioRxiv : the preprint server for biology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rohan S WakadeDepartment of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Juraj KramaraDepartment of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Melanie WellingtonDepartment of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Damian J KrysanDepartment of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0001-6330-3365
University of Iowa · US

Funding

Complex haploinsufficiency based genetic analysis of C. albicans pathogenesisR01AI133409 · NIAID · UNIVERSITY OF IOWA · PI KRYSAN, DAMIAN J · 2018 to 2022
$2.5M
Systematic in vitro and in vivo genetic analysis of C.albicans protein kinasesR21AI157341 · NIAID · UNIVERSITY OF IOWA · PI KRYSAN, DAMIAN J · 2021 to 2022
$436k
NIAID NIH HHS R01 AI133409NIAID NIH HHS R21 AI157341
6 · The paper itself

Abstract

Candida albicans is one of the most prevalent human fungal pathogens. Its ability to transition between budding yeast and filamentous morphological forms (pseudohyphae and hyphae) is tightly associated with its pathogenesis. Based on

Indexed as

Candida albicansCyclic AMP-Dependent Protein KinasesFungal ProteinsGene Expression Regulation, FungalHyphaeCyclic AMP-Dependent Protein KinasesFungal ProteinsCandida albicanscyclic AMPfungal pathogenesishyphaeNFAT transcription factorsprotein kinase A

Identifiers

PMID35475642
PMCPMC9239198
OpenAlexW4225000371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.