Evidence map›Paper›PMID 35475626›Full record

ArticleMicrobiology spectrum2022

Fecal Microbial Community Composition in Myeloproliferative Neoplasm Patients Is Associated with an Inflammatory State.

Andrew Oliver, Kenza El Alaoui, Carolyn Haunschild, Julio Avelar-Barragan, Laura F Mendez Luque, Katrine Whiteson, Angela G Fleischman

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Andrew Oliver *Department of Molecular Biology and Biochemistry, School of Biological Sciences, University of California Irvine, Irvine, California, USA.ORCID 0000-0001-7731-6925
Kenza El Alaoui *Division of Hematology/Oncology, School of Medicine, University of California Irvine, Irvine, California, USA.
Carolyn HaunschildDivision of Gynecologic Oncology, School of Medicine, University of California Irvine, Irvine, California, USA.
Julio Avelar-BarraganDepartment of Molecular Biology and Biochemistry, School of Biological Sciences, University of California Irvine, Irvine, California, USA.
Laura F Mendez LuqueBiological Chemistry, School of Medicine, University of California Irvine, Irvine, California, USA.
Katrine WhitesonDepartment of Molecular Biology and Biochemistry, School of Biological Sciences, University of California Irvine, Irvine, California, USA.ORCID 0000-0002-5423-6014
Angela G FleischmanDivision of Hematology/Oncology, School of Medicine, University of California Irvine, Irvine, California, USA.ORCID 0000-0002-3701-6079
University of California, Irvine · USUniversité Libre de Bruxelles · BE

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
INSTITUTIONAL NATIONAL RESEARCH SERVICE AWARDT32CA060396 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI BRISTOW, ROBERT EDWARD · 1994 to 2020
$4.6M
NCI NIH HHS P30 CA062203NCI NIH HHS T32 CA060396
6 · The paper itself

Abstract

The capacity of the human microbiome to modulate inflammation in the context of cancer is becoming increasingly clear. Myeloproliferative neoplasms (MPNs) are chronic hematologic malignancies in which inflammation plays a key role in disease initiation, progression, and symptomatology. To better understand the composition of the gut microbiome in patients with MPN, triplicate fecal samples were collected from 25 MPN patients and 25 non-MPN controls. Although most of the variance between the microbial community compositions could be attributed to the individual (permutational analysis of variance [PERMANOVA],

Indexed as

Gastrointestinal MicrobiomeMyeloproliferative DisordersNeoplasmsChronic DiseaseFecesHumansInflammationcytokinesinflammationmicrobiomemyeloproliferative neoplasm

Identifiers

PMID35475626
PMCPMC9241690
OpenAlexW4224988987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.