ReviewJournal of human nutrition and dietetics : the official journal of the British Dietetic Association2022
Early life programming of health and disease: The long-term consequences of obesity in pregnancy.
Review in Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Pooled it
- Child somatic growth and neurodevelopment: effects of pregnancy lifestyle intervention.Pediatric research · 2025Trial
- Article
- The Contribution of Ultrasound and Doppler Studies on Impaired Intrauterine Conditions and the Development of Future Disease.Medicina (Kaunas, Lithuania) · 2026Review
- Maternal Mediterranean Diet during Pregnancy and Adiposity from Early Childhood through Preadolescence.Childhood obesity (Print) · 2026Article
- Article
- Maternal Overnutrition and Fetal Programming: Long-Term Metabolic, Cognitive, and Epigenetic Consequences.Cells · 2026Review
- Dietary index for gut microbiota and odds of gestational diabetes mellitus: associations with inflammatory and metabolic biomarkers.Frontiers in nutrition · 2026Article
- Developmental origins of immunometabolic health.Immunometabolism (Cobham, Surrey) · 2026Review
- Gestational Weight Gain as a Modifiable Risk Factor in Women with Extreme Pregestational BMI.Nutrients · 2025Review
- Metabolomic and transcriptomic remodeling of bone marrow myeloid cells in response to maternal obesity.American journal of physiology. Endocrinology and metabolism · 2025Article
- Maternal lipids in overweight and obesity: implications for pregnancy outcomes and offspring's body composition.Seminars in immunopathology · 2025Review
- Women's experiences of high-risk pregnancy care in resource constrained Cape Town communities.Health SA = SA Gesondheid · 2025Article
- Metabolic abnormalities in the bone marrow cells of young offspring born to mothers with obesity.International journal of obesity (2005) · 2024Article
- Maternal Synbiotic Supplementation withNutrients · 2024Article
- Pregestational Prediabetes Induces Maternal Hypothalamic-Pituitary-Adrenal (HPA) Axis Dysregulation and Results in Adverse Foetal Outcomes.International journal of molecular sciences · 2024Article
- An overview of the nutritional status of childbearing age women, children and adolescents living in a rural area of Madagascar: preliminary results of the Tany Vao project.Public health nutrition · 2024Article
- Metabolic abnormalities in the bone marrow cells of young offspring born to obese mothers.Research square · 2024Article
- Programming of metabolism by adipokines during development.Nature reviews. Endocrinology · 2023Review
- Pregnant Women's Perception and Knowledge of the Impact of Obesity on Prenatal Outcomes-A Cross-Sectional Study.Nutrients · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of overweight and obesity is rising in all parts of the world and, among young women, it presents a very clear danger during pregnancy. Women who are overweight or who gain excessive weight during pregnancy are at greater risk of complications in pregnancy and labour, and are more likely to lose their child to stillbirth or die themselves during pregnancy. This narrative review considers the evidence that, in addition to increasing risk of poor pregnancy outcomes, obesity has the capacity to programme foetuses to be at greater risk of cardiometabolic disorders later in life. An extensive body of evidence from prospective and retrospective cohorts, as well as record linkage studies, demonstrates associations of maternal obesity and/or gestational diabetes with cardiovascular disease, as well as type 1 and type 2 diabetes. Studies in animals suggest that these associations are underpinned by adaptations that occur in foetal life, which remodel the structures of major organs, including the brain, kidney and pancreas.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.