Evidence map›Paper›PMID 35475384›Full record

ArticleDrug delivery2022

Chidamide stacked in magnetic polypyrrole nano-composites counter thermotolerance and metastasis for visualized cancer photothermal therapy.

Sizhen Wang, Zhiqiang Ma, Zhang Shi, Ying Huang, Tianheng Chen, Lei Hou, Tao Jiang, Feng Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug delivery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sizhen WangDepartment of Inorganic Chemistry, Pharmacy School, Naval Medical University School, Shanghai, PR China.
Zhiqiang MaDepartment of Inorganic Chemistry, Pharmacy School, Naval Medical University School, Shanghai, PR China.
Zhang ShiDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai, PR China.
Ying HuangDepartment of Inorganic Chemistry, Pharmacy School, Naval Medical University School, Shanghai, PR China.
Tianheng ChenDepartment of Inorganic Chemistry, Pharmacy School, Naval Medical University School, Shanghai, PR China.
Lei HouDepartment of Inorganic Chemistry, Pharmacy School, Naval Medical University School, Shanghai, PR China.
Tao JiangDepartment of Nuclear Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, PR China.
Feng YangDepartment of Inorganic Chemistry, Pharmacy School, Naval Medical University School, Shanghai, PR China.
Fujian University of Traditional Chinese Medicine · CNTongji University · CNZhongshan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photothermal therapy (PTT) has become one of the most promising therapies in cancer treatment as its noninvasiveness, high selectivity, and favorable compliance in clinic. However, tumor thermotolerance and distal metastasis reduce its efficacy, becoming the bottleneck of applying PTT in clinic. In this study, a chidamide-loaded magnetic polypyrrole nanocomposite (CMPP) has been fabricated as a visualized cancer photothermal agent (PTA) to counter tumor thermotolerance and metastasis. The efficacy of CMPP was characterized by

Indexed as

NeoplasmsThermotoleranceAminopyridinesAnimalsBenzamidesMagnetic Resonance ImagingMicePhototherapyPhotothermal TherapyPolymersPyrrolesAminopyridinesBenzamidesN-(2-amino-5-fluorobenzyl)-4-(N-(pyridine-3-acrylyl)aminomethyl)benzamidePolymerspolypyrrolePyrrolesdual-modal imagingMagnetic targeting nanocomplexphotothermal therapypolypyrrolesynergistic treatment

Identifiers

PMID35475384
PMCPMC9067950
OpenAlexW4224940981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.