Evidence map›Paper›PMID 35475302›Full record

ArticleBJUI compass2021

Pitcher pot neourethral modification of ileal orthotopic neobladder achieves satisfactory long-term functional and quality of life outcomes with low clean intermittent self-catheterization rate.

Jiten Jaipuria, Ahmad Mamoon Karimi, Amitabh Singh, Bikash Bikram Thapa, Shashikant Gupta, Nripesh Sadasukhi, Manikandan Venkatasubramaniyan, Preeti Pathak, Priyatham Kasaraneni, Ashish Khanna and 3 more

Abstract read
In one paragraph

Article in BJUI compass, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jiten JaipuriaAmity Centre for Cancer Epidemiology & Cancer Research Amity Institute of Biotechnology Amity University Uttar Pradesh Noida India.ORCID https://orcid.org/0000-0003-3223-8155
Ahmad Mamoon KarimiDepartment of Surgical Oncology Uro-oncology Division Rajiv Gandhi Cancer Institute and Research Centre New Delhi India.
Amitabh SinghDepartment of Surgical Oncology Uro-oncology Division Rajiv Gandhi Cancer Institute and Research Centre New Delhi India.ORCID https://orcid.org/0000-0002-8180-1891
Bikash Bikram ThapaDepartment of Surgical Oncology Uro-oncology Division Rajiv Gandhi Cancer Institute and Research Centre New Delhi India.
Shashikant GuptaDepartment of Surgical Oncology Uro-oncology Division Rajiv Gandhi Cancer Institute and Research Centre New Delhi India.
Nripesh SadasukhiDepartment of Surgical Oncology Uro-oncology Division Rajiv Gandhi Cancer Institute and Research Centre New Delhi India.
Manikandan VenkatasubramaniyanDepartment of Surgical Oncology Uro-oncology Division Rajiv Gandhi Cancer Institute and Research Centre New Delhi India.
Preeti PathakDepartment of Surgical Oncology Uro-oncology Division Rajiv Gandhi Cancer Institute and Research Centre New Delhi India.
Priyatham KasaraneniDepartment of Surgical Oncology Uro-oncology Division Rajiv Gandhi Cancer Institute and Research Centre New Delhi India.
Ashish KhannaDepartment of Surgical Oncology Uro-oncology Division Rajiv Gandhi Cancer Institute and Research Centre New Delhi India.ORCID https://orcid.org/0000-0002-9114-6739
Tushar Aditya NarayanDepartment of Surgical Oncology Uro-oncology Division Rajiv Gandhi Cancer Institute and Research Centre New Delhi India.
Girish SharmaCentre for Medical Biotechnology, Coordinator Amity Centre for Cancer Epidemiology & Cancer Research Amity Institute of Biotechnology Amity University Uttar Pradesh Noida India.ORCID https://orcid.org/0000-0003-2127-5700
Sudhir RawalDepartment of Surgical Oncology Uro-oncology Division Rajiv Gandhi Cancer Institute and Research Centre New Delhi India.ORCID https://orcid.org/0000-0002-3331-2372

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To describe a decade of our experience with a neo-urethral modification of ileal orthotopic neobladder (pitcher pot ONB). Multiple investigators have reported similar modifications. However, long-term longitudinal functional and quality of life (QOL) outcomes are lacking. Methods: Prospectively maintained hospital registry for 238 ONB patients comprising a mix of open and robotic surgery cohorts from 2007 to 2017, and minimum of 2 years of follow-up was retrospectively queried. QOL was evaluated using Bladder Cancer Index (BCI). Longitudinal trends of QOL domain parameters were analysed. List of perioperative variables that have a biologically plausible association with continence, potency, and post-operative BCI QOL sexual, urinary, and bowel domain scores was drawn. Variables included surgery type, Body Mass Index (BMI), T and N stage, neurovascular bundle (NVB) sparing, age, and related pre-operative BCI QOL domain score. Prognostic associations were analysed using multivariable Cox proportional hazard models and multilevel mixed-effects modeling. Results: The study comprised 80 and 158 patients who underwent open and robotic sandwich technique cohorts, respectively. Open surgery was associated with significantly higher "any" complication (40% vs 27%, Conclusions: Pitcher pot neobladder achieves satisfactory long-term functional and QOL outcomes with negligible CISC rate. Results were superior with incremental nerves spared during surgery.

Indexed as

neobladderquality of liferadical cystectomyrobot‐assisted radical cystectomyurinary bladder neoplasmsurinary diversionurinary incontinence

Identifiers

PMID35475302
PMCPMC8988529

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.