Evidence map›Paper›PMID 35475293›Full record

ArticleBiocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al2022

Synergy of single-cell sequencing analyses and

Yuki Matsushita, Wanida Ono, Noriaki Ono

Abstract read
In one paragraph

Article in Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Bone marrow adipocytes: key players in vascular niches, aging, and disease.Frontiers in cell and developmental biology · 2025
    Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Cranial Base Synchondrosis: Chondrocytes at the Hub.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuki MatsushitaUniversity of Texas Health Science Center at Houston School of Dentistry, Houston, 77054, USA.
Wanida OnoUniversity of Texas Health Science Center at Houston School of Dentistry, Houston, 77054, USA.
Noriaki OnoUniversity of Texas Health Science Center at Houston School of Dentistry, Houston, 77054, USA.

Funding

Craniofacial skeletal cell lineage plasticity for reconstituting stem cells and their nichesR01DE030630 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ONO, NORIAKI, ONO, WANIDA · 2021 to 2025
$2.2M
Dynamics and Regulations of Bone Stem Cells in VivoR01DE026666 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ONO, NORIAKI · 2018 to 2022
$2.1M
Dental Follicle: A Central Regulator of Tooth Root Formation and RegenerationR01DE029181 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ONO, WANIDA · 2021 to 2025
$1.9M
NIDCR NIH HHS R01 DE026666NIDCR NIH HHS R01 DE029181NIDCR NIH HHS R01 DE030630
6 · The paper itself

Abstract

Single-cell sequencing technologies have rapidly progressed in recent years, and been applied to characterize stem cells in a number of organs. Somatic (postnatal) stem cells are generally identified using combinations of cell surface markers and transcription factors. However, it has been challenging to define micro-heterogeneity within "stem cell" populations, each of which stands at a different level of differentiation. As stem cells become defined at a single-cell level, their differentiation path becomes clearly defined. Here, this viewpoint discusses the potential synergy of single-cell sequencing analyses with

Indexed as

bone marrow stromal cells (BMSCs)in vivo lineage-lineagemesenchymal stem cells (MSCs)Single-cell sequencingskeletal stem cells (SSCs)

Identifiers

PMID35475293
PMCPMC9037299

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.