Evidence map›Paper›PMID 35475288›Full record

ArticleMaterials today. Chemistry2022

Influence of particle size on the SARS-CoV-2 spike protein detection using IgG-capped gold nanoparticles and dynamic light scattering.

C B P Ligiero, T S Fernandes, D L D'Amato, F V Gaspar, P S Duarte, M A Strauch, J G Fonseca, L G R Meirelles, P Bento da Silva, R B Azevedo and 6 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

C B P LigieroDepartamento de Química Inorgânica, Universidade Federal Fluminense (UFF), Campus Do Valonguinho, Outeiro de São João Batista, S/n, 24020-141, Niterói, RJ, Brazil.
T S FernandesDepartamento de Química Inorgânica, Universidade Federal Fluminense (UFF), Campus Do Valonguinho, Outeiro de São João Batista, S/n, 24020-141, Niterói, RJ, Brazil.
D L D'AmatoDepartamento de Química Inorgânica, Universidade Federal Fluminense (UFF), Campus Do Valonguinho, Outeiro de São João Batista, S/n, 24020-141, Niterói, RJ, Brazil.
F V GasparDepartamento de Química Inorgânica, Universidade Federal Fluminense (UFF), Campus Do Valonguinho, Outeiro de São João Batista, S/n, 24020-141, Niterói, RJ, Brazil.
P S DuarteDepartamento de Química, Pontifícia Universidade Católica Do Rio de Janeiro (PUC-Rio), Rio de Janeiro, RJ, 22451-900, Brazil.
M A StrauchGerência de Desenvolvimento Tecnológico, Instituto Vital Brazil, Niterói, RJ, 24230-410, Brazil.
J G FonsecaGerência de Desenvolvimento Tecnológico, Instituto Vital Brazil, Niterói, RJ, 24230-410, Brazil.
L G R MeirellesFazenda Instituto Vital Brazil, Niterói, RJ, 24230-410, Brazil.
P Bento da SilvaDepartamento de Genética e Morfologia, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, 70910-900, Brazil.
R B AzevedoDepartamento de Genética e Morfologia, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, 70910-900, Brazil.
G Aparecida de Souza MartinsPrograma de Pós-graduação Em Ciência e Tecnologia de Alimentos, Universidade Federal Do Tocantins, 77001-090, Brazil.
B S ArchanjoDivisão de Metrologia de Materiais, Instituto Nacional de Metrologia, Qualidade e Tecnologia (Inmetro), Duque de Caxias, RJ, 25250-020, Brazil.
C D BuarqueDepartamento de Química, Pontifícia Universidade Católica Do Rio de Janeiro (PUC-Rio), Rio de Janeiro, RJ, 22451-900, Brazil.
G MachadoCentro de Tecnologias Estratégicas Do Nordeste, Av. Prof. Luiz Freire 01, Recife, Pernambuco, 50740-540, Brazil.
A M PercebomDepartamento de Química, Pontifícia Universidade Católica Do Rio de Janeiro (PUC-Rio), Rio de Janeiro, RJ, 22451-900, Brazil.
C M RonconiDepartamento de Química Inorgânica, Universidade Federal Fluminense (UFF), Campus Do Valonguinho, Outeiro de São João Batista, S/n, 24020-141, Niterói, RJ, Brazil.
Universidade Federal Fluminense · BRInstituto Vital Brazil (Brazil) · BRPontifícia Universidade Católica do Rio de Janeiro · BRUniversidade de Brasília · BRCentro de Tecnologias Estratégicas do Nordeste · BRInstituto Nacional de Metrologia, Qualidade e Tecnologia · BRUniversidade Federal do Tocantins · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the unprecedented and ongoing nature of the coronavirus outbreak, the development of rapid immunoassays to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its highly contagious variants is an important and challenging task. Here, we report the development of polyclonal antibody-functionalized spherical gold nanoparticle biosensors as well as the influence of the nanoparticle sizes on the immunoassay response to detect the SARS-CoV-2 spike protein by dynamic light scattering. By monitoring the increment in the hydrodynamic diameter (ΔD

Indexed as

Dynamic light scatteringGold nanoparticles size effectImmunoassaySARS-CoV-2 spike protein

Identifiers

PMID35475288
PMCPMC9023328
OpenAlexW4224294706

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.