Evidence map›Paper›PMID 35475223›Full record

ArticleCell reports methods2022

A taste of the early steps in BAX activation with FLAMBE.

Melanie Gil, Marina R Hanna, Vivian Gama

Open access · goldAbstract readComment
In one paragraph

Article in Cell reports methods, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Melanie GilDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.
Marina R HannaDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.
Vivian GamaDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.
Vanderbilt University · US

Funding

Training in Fundamental NeuroscienceT32MH064913 · NIMH · VANDERBILT UNIVERSITY · PI IHRIE, REBECCA A, WINDER, DANNY G. · 2001 to 2022
$7.6M
Training Program in Stem Cell and Regenerative Developmental BiologyT32HD007502 · NICHD · VANDERBILT UNIVERSITY · PI WRIGHT, CHRISTOPHER V · 1997 to 2022
$5.4M
The BCL-2 family controls stem cell identity by regulating mitochondrial dynamics and primingR35GM128915 · NIGMS · VANDERBILT UNIVERSITY · PI Vivian Gama · 2018 to 2026
$3.8M
Modeling developmental gradients and supportive tissue signaling networks using iPSC-derived forebrain organoids embedded in fluidic hydrogelsRF1MH123971 · NIMH · VANDERBILT UNIVERSITY · PI BELLAN, LEON MARCEL, GAMA, VIVIAN · 2020 to 2020
$2.3M
NICHD NIH HHS T32 HD007502NIGMS NIH HHS R35 GM128915NIMH NIH HHS RF1 MH123971NIMH NIH HHS T32 MH064913
6 · The paper itself

Abstract

The activation of BAX through intricate intramolecular changes is critical for apoptosis. In this issue of

Indexed as

ApoptosisTastebcl-2-Associated X ProteinFluorescence PolarizationLigandsbcl-2-Associated X ProteinLigands

Identifiers

PMID35475223
PMCPMC9017131
OpenAlexW4220959123

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.