Evidence map›Paper›PMID 35475201›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2022

Effects of SGLT2 inhibitor on tumor-releasing chemokines/cytokines in Hep3B and Huh7 cells.

Dan Nakano, Takumi Kawaguchi, Tsubasa Tsutsumi, Masako Hayakawa, Sachiyo Yoshio, Hironori Koga, Takuji Torimura

Open access · goldAbstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Dan NakanoDivision of Gastroenterology, Department of Medicine Kurume University School of Medicine Kurume Japan.ORCID https://orcid.org/0000-0001-6098-1224
Takumi KawaguchiDivision of Gastroenterology, Department of Medicine Kurume University School of Medicine Kurume Japan.ORCID https://orcid.org/0000-0002-7064-4325
Tsubasa TsutsumiDivision of Gastroenterology, Department of Medicine Kurume University School of Medicine Kurume Japan.ORCID https://orcid.org/0000-0001-6571-9874
Masako HayakawaLiver Cancer Division, Research Center for Innovative Cancer Therapy Kurume University Kurume Japan.
Sachiyo YoshioDepartment of Liver Disease Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine Kohnodai Japan.ORCID https://orcid.org/0000-0001-7860-6916
Hironori KogaDivision of Gastroenterology, Department of Medicine Kurume University School of Medicine Kurume Japan.ORCID https://orcid.org/0000-0001-5814-9543
Takuji TorimuraDivision of Gastroenterology, Department of Medicine Kurume University School of Medicine Kurume Japan.ORCID https://orcid.org/0000-0002-4863-4278
Kurume University · JPNational Center for Global Health and Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(a) Summary for SGLT2i-induced alterations in 48 chemokines/cytokines in Hep3B and Huh7 cells. (b) SGLT2i-induced changes in the medium CXCL1 level (each

Indexed as

chemokinecytokinehepatomasodium‐glucose cotransporter 2tumor microenvironment

Identifiers

PMID35475201
PMCPMC9021706
OpenAlexW4220950570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.