Evidence map›Paper›PMID 35475008›Full record

ArticleAME case reports2022

New onset systemic lupus erythematosus after COVID-19 infection: a case report.

Lintu Ramachandran, Venkata Satish Dontaraju, James Troyer, Jagpal Sahota

Open access · diamondAbstract readCase Reports
In one paragraph

Article in AME case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Late-onset Systemic Lupus Erythematosus.Rheumatology international · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Long COVID in autoimmune rheumatic diseases.Rheumatology international · 2023
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lintu RamachandranDepartment of Internal Medicine, Mercyhealth Javon Bea Hospital, Rockford, IL, USA.
Venkata Satish DontarajuDepartment of Internal Medicine, Mercyhealth Javon Bea Hospital, Rockford, IL, USA.
James TroyerDepartment of Internal Medicine, Mercyhealth Javon Bea Hospital, Rockford, IL, USA.
Jagpal SahotaDepartment of Internal Medicine, Mercyhealth Javon Bea Hospital, Rockford, IL, USA.
Javon Bea Hospital-Rockton · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 is a respiratory viral illness that can have life threatening complications. While the short-term sequela of COVID-19, including cytokine storm, is relatively well known, the long-term complications of COVID-19 infection on the immune system is still unknown. There have been some reported cases of autoimmune disease development after COVID-19 infection. We present a patient with a history of COVID-19 infection one month prior who presented with non-specific symptoms including fatigue, malaise, bilateral lower extremity swelling and shortness of breath. His laboratory evaluation and physical exam showed him to be in acute renal failure. Further workup and kidney biopsy results confirmed systemic lupus erythematosus (SLE). Our patient needed treatment with plasmapheresis and immunosuppressants, and subsequently had significant improvement in his symptoms. We discuss the current 2019 European Alliance of Associations for Rheumatology/American College of Rheumatology (EULAR/ACR) diagnostic criteria for SLE and describe plausible mechanisms of COVID-19 induced lupus such as B-cell activation by the virus. We also explore the role of interferons in the potential development of autoimmune diseases after COVID-19 infection and highlight the need for further research in the area.

Indexed as

autoimmunity after infectioncase reportCOVID-19Systemic lupus erythematosus (SLE)

Identifiers

PMID35475008
PMCPMC9010314
OpenAlexW4205359630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.