Evidence map›Paper›PMID 35474470›Full record

ArticleGlia2022

Functional adaptation of glial cells at neuromuscular junctions in response to injury.

Anna P Perez-Gonzalez, Frédéric Provost, Isabelle Rousse, Roberta Piovesana, Ouafa Benzina, Houssam Darabid, Benoit Lamoureux, Yu Shi Wang, Danielle Arbour, Richard Robitaille

Open access · hybridAbstract read
In one paragraph

Article in Glia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Review of the Pathology of Muscle in Amyotrophic Lateral Sclerosis.International journal of molecular sciences · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. The Neuromuscular Junction: A Shared Vulnerability in Aging and Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Skeletal muscle in amyotrophic lateral sclerosis.Brain : a journal of neurology · 2023
    Review
  13. Article
  14. Synaptic Dysfunction and Plasticity in Amyotrophic Lateral Sclerosis.International journal of molecular sciences · 2023
    Review
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Anna P Perez-GonzalezDépartement de Neurosciences, Université de Montréal, Montréal, Québec, Canada.ORCID 0000-0002-5588-8233
Frédéric ProvostDépartement de Neurosciences, Université de Montréal, Montréal, Québec, Canada.ORCID 0000-0002-2432-7580
Isabelle RousseDépartement de Neurosciences, Université de Montréal, Montréal, Québec, Canada.
Roberta PiovesanaDépartement de Neurosciences, Université de Montréal, Montréal, Québec, Canada.
Ouafa BenzinaDépartement de Neurosciences, Université de Montréal, Montréal, Québec, Canada.
Houssam DarabidDépartement de Neurosciences, Université de Montréal, Montréal, Québec, Canada.
Benoit LamoureuxDépartement de Neurosciences, Université de Montréal, Montréal, Québec, Canada.
Yu Shi WangDépartement de Neurosciences, Université de Montréal, Montréal, Québec, Canada.
Danielle ArbourDépartement de Neurosciences, Université de Montréal, Montréal, Québec, Canada.ORCID 0000-0002-7268-1488
Richard RobitailleDépartement de Neurosciences, Université de Montréal, Montréal, Québec, Canada.ORCID 0000-0001-6628-0146
Université de Montréal · CACentre for Interdisciplinary Research in Rehabilitation · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synaptic elements from neuromuscular junctions (NMJs) undergo massive morphological and functional changes upon nerve injury. While morphological changes of NMJ-associated glia in response to injury has been investigated, their functional properties remain elusive. Perisynaptic Schwann cells (PSCs), glial cells at the NMJ, are essential for NMJ maintenance and repair, and are involved in synaptic efficacy and plasticity. Importantly, these functions are regulated by PSCs ability to detect synaptic transmission through, notably, muscarinic (mAChRs) and purinergic receptors' activation. Using Ca

Indexed as

Amyotrophic Lateral SclerosisAnimalsCholinergic AgentsMiceNeurogliaNeuromuscular JunctionSchwann CellsSuperoxide Dismutase-1Cholinergic AgentsSuperoxide Dismutase-1amyotrophic lateral sclerosisdenervationmuscarinic receptorsneuromuscular junctionperisynaptic Schwann cellspurinergic receptorsreinnervation

Identifiers

PMID35474470
PMCPMC9543218
OpenAlexW4224922672

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.