ArticleNature communications2022
T cell receptor and IL-2 signaling strength control memory CD8
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In one paragraph
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed.
- Tebentafusp, a T cell engager, promotes macrophage reprogramming and in combination with IL-2 overcomes macrophage immunosuppression in cancer.Nature communications · 2025Trial
- Oral Food-Derived Proanthocyanidins as Immunostimulants: Enhanced Vaccine Immunogenicity via Host Immune Modulation in a Murine CSFV Model.Molecules (Basel, Switzerland) · 2026Article
- Review
- Nanoparticle induction of antigen-presenting monocyte-derived dendritic cells relieves immunosuppression and inhibits metastasis.Cell biomaterials · 2026Article
- Tumor-targeted IL2 promotes specific CD8Journal of experimental & clinical cancer research : CR · 2026Article
- HIV- and cytomegalovirus-specific human memory CD8+ T cells are activated and expanded independent of co-stimulatory signaling by T-cell receptor-specific immunotherapeutics.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- An early burst of cytokine production before the first cell division influences CD8 T cell differentiation.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Immune Dysregulation in HIV-TB Co-Infection: Role of Cytokines and T Cell Biomarkers-A Narrative Review.Pathogens (Basel, Switzerland) · 2026Review
- Protective Immunity Induced by DNA Vaccines Encoding TgGRA47 and TgGRA72 AgainstTransboundary and emerging diseases · 2026Article
- Thymopentin Enhances Antitumor Immunity Through Thymic Rejuvenation and T Cell Functional Reprogramming.Biomedicines · 2025Article
- Zeaxanthin augments CD8Cell reports. Medicine · 2025Article
- Properties of CD8 T-cell-recognized neoantigens in different tumor types.Immuno-oncology technology · 2025Article
- H2A.Z primes an epigenetic landscape for memory CD8Nature communications · 2025Article
- Unveiling Immune Response Mechanisms in Mpox Infection Through Machine Learning Analysis of Time Series Gene Expression Data.Life (Basel, Switzerland) · 2025Article
- IL-2 immunotherapy rescues irradiation-induced T cell exhaustion in mouse colon cancer.iScience · 2025Article
- Androgens inhibit protective CD8Nature communications · 2025Article
- Metal-modulated T cell antitumor immunity and emerging metalloimmunotherapy.Cancer metastasis reviews · 2025Review
- Epigenetic regulators combined with tumour immunotherapy: current status and perspectives.Clinical epigenetics · 2025Review
- Multilayer Adjuvanted Influenza Protein Nanoparticles Improve Intranasal Delivery and Antigen-Specific Immunity.ACS nano · 2025Article
- APMAT analysis reveals the association between CD8 T cell receptors, cognate antigen, and T cell phenotype and persistence.Nature communications · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Shu Shien Chin *Albert Einstein College of Medicine, Department of Microbiology and Immunology, Bronx, NY, 10461, USA.ORCID 0000-0002-2455-9533
Erik Guillen *Albert Einstein College of Medicine, Department of Microbiology and Immunology, Bronx, NY, 10461, USA.
Laurent ChorroAlbert Einstein College of Medicine, Department of Microbiology and Immunology, Bronx, NY, 10461, USA.
Sooraj AcharNational Cancer Institute, Cancer & Inflammation Program, Center for Cancer Research, ImmunoDynamics Group, Bethesda, MD, 20892, USA.
Karina NgAlbert Einstein College of Medicine, Department of Microbiology and Immunology, Bronx, NY, 10461, USA.
Susanne OberleDivision of Animal Physiology and Immunology, School of Life Sciences Weihenstephan, Technical University of Munich, 85354, Freising, Germany.
Francesca AlfeiDivision of Animal Physiology and Immunology, School of Life Sciences Weihenstephan, Technical University of Munich, 85354, Freising, Germany.
Dietmar ZehnDivision of Animal Physiology and Immunology, School of Life Sciences Weihenstephan, Technical University of Munich, 85354, Freising, Germany.ORCID 0000-0003-1393-8527
Grégoire Altan-BonnetNational Cancer Institute, Cancer & Inflammation Program, Center for Cancer Research, ImmunoDynamics Group, Bethesda, MD, 20892, USA.ORCID 0000-0002-9602-8133
Fabien DelahayeAlbert Einstein College of Medicine, Department of Genetics, Bronx, NY, 10461, USA. fabien.delahaye@pasteur-lille.fr.ORCID 0000-0002-9921-8653
Grégoire LauvauAlbert Einstein College of Medicine, Department of Microbiology and Immunology, Bronx, NY, 10461, USA. gregoire.lauvau@einsteinmed.org.ORCID 0000-0002-3050-2664
Funding
WORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI THOMAS E ROHAN · 1985 to 2026
$111.2MMEDICAL SCIENTIST TRAINING PROGRAMT32GM007288 · NIGMS · YESHIVA UNIVERSITY · PI AKABAS, MYLES H. · 1985 to 2022
$35.6MEnhancing Pathogen-specific Memory CD8+ T cell Responses in VivoR01AI103338 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI LAUVAU, GREGOIRE STEPHANE · 2013 to 2022
$5.2MGeographic Medicine and Emerging InfectionsT32AI070117 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI WEISS, LOUIS M. · 2008 to 2023
$5.1MPhenotypic variability within isogenic population of lymphocytesZIABC011726 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ALTAN-BONNET, GRÉGOIRE · 2016 to 2025
$3.9MCytokine coordination of collective immune responses against tumorsZIABC011728 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ALTAN-BONNET, GREGOIRE · 2016 to 2023
$3.7MEnhancing Pathogen-Specific Memory CD8+ T cell Responses In VivoR56AI103338 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI LAUVAU, GREGOIRE STEPHANE · 2024 to 2024
$633kNCI NIH HHS P30 CA013330NIAID NIH HHS R01 AI103338NIAID NIH HHS R56 AI103338NIAID NIH HHS T32 AI070117NIGMS NIH HHS T32 GM007288
Abstract
Cognate antigen signal controls CD8
Indexed as
Biological PhenomenaInterleukin-2AntigensCalciumCD8-Positive T-LymphocytesChromatinChromatin Assembly and DisassemblyImmunologic MemoryReceptors, Antigen, T-CellAntigensCalciumChromatinInterleukin-2Receptors, Antigen, T-Cell
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.