Evidence map›Paper›PMID 35474079›Full record

ArticleNPJ vaccines2022

Self-adjuvanting nanovaccines boost lung-resident CD4

Megan A Files, Kubra F Naqvi, Tais B Saito, Tara M Clover, Jai S Rudra, Janice J Endsley

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Substituent-Based Modulation of Self-Assembly and Immunogenicity of Amphipathic Peptides.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Megan A FilesDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, 77555, USA.ORCID http://orcid.org/0000-0002-5064-0490
Kubra F NaqviDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.ORCID http://orcid.org/0000-0003-4703-9466
Tais B SaitoDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, 77555, USA.
Tara M CloverComprehensive Industrial Hygiene Laboratory (CIHL), Navy Environmental and Preventive Medicine Unit TWO (NEPMU-2), Department of the Navy, Norfolk, VA, 23551, USA.
Jai S RudraDepartment of Biomedical Engineering, McKelvey School of Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA. srudra22@wustl.edu.ORCID http://orcid.org/0000-0002-7837-4980
Janice J EndsleyDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, 77555, USA. jjendsle@utmb.edu.ORCID http://orcid.org/0000-0002-3883-8250

Funding

Immunomodulatory Effects of Heterochiral BiomaterialsR01AI130278 · NIAID · WASHINGTON UNIVERSITY · PI RUDRA, JAI · 2018 to 2022
$1.8M
Self-assembling Peptide Nanomaterials for Eliciting Mucosal CD8+ T cell ImmunityR21AI115302 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI ENDSLEY, JANICE J, RUDRA, JAI · 2016 to 2017
$416k
NIAID NIH HHS R01 AI130278NIAID NIH HHS R21 AI115302
6 · The paper itself

Abstract

Heterologous vaccine regimens could extend waning protection in the global population immunized with Mycobacterium bovis Bacille Calmette-Guerin (BCG). We demonstrate that pulmonary delivery of peptide nanofibers (PNFs) bearing an Ag85B CD4

Identifiers

PMID35474079
PMCPMC9043212

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.