Evidence map›Paper›PMID 35473926›Full record

ArticleNature communications2022

An osmium-peroxo complex for photoactive therapy of hypoxic tumors.

Nong Lu, Zhihong Deng, Jing Gao, Chao Liang, Haiping Xia, Pingyu Zhang

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Gold(I)ACS medicinal chemistry letters · 2025
    Article
  8. The Aromaticity of Osmapentalenes Derivatives - An Analysis Based on Electron-Delocalization Indices.Chemphyschem : a European journal of chemical physics and physical chemistry · 2025
    Article
  9. Recent Advances in Anticancer Research of Osmium and Rhodium Complexes.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2025
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. [FeMolecules (Basel, Switzerland) · 2024
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Nong Lu *College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China.
Zhihong Deng *Shenzhen Grubbs Institute, Department of Chemistry, Southern University of Science and Technology, Shenzhen, 518055, China.ORCID 0000-0002-1982-2616
Jing GaoShenzhen Grubbs Institute, Department of Chemistry, Southern University of Science and Technology, Shenzhen, 518055, China.
Chao LiangCollege of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China.
Haiping XiaShenzhen Grubbs Institute, Department of Chemistry, Southern University of Science and Technology, Shenzhen, 518055, China. hpxia@xmu.edu.cn.ORCID 0000-0002-2688-6634
Pingyu ZhangCollege of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China. p.zhang6@szu.edu.cn.ORCID 0000-0002-2921-9490
Shenzhen University · CNSouthern University of Science and Technology · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The limited therapeutic effect on hypoxic and refractory solid tumors has hindered the practical application of photodynamic therapy. Herein, we report our investigation of an osmium-peroxo complex (Os2), which is inactive in the dark, but can release a peroxo ligand O

Indexed as

Antineoplastic AgentsNeoplasmsPhotochemotherapyAnimalsHypoxiaMiceOsmiumOxygenAntineoplastic AgentsOsmiumOxygen

Identifiers

PMID35473926
PMCPMC9042834
OpenAlexW4225253407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.