ArticleNature communications2022
Knockdown of GABA
Open access · goldAbstract read
In one paragraph
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 29 citations in OpenAlex.
- Dyscoordination of thalamic reticular spindles is associated with social memory deficits in mice and humans with autism spectrum disorder.Nature communications · 2026Article
- Loss of connexin 36 elicits abnormalities in thalamocortical network activity relevant to neuropsychiatric disorders.Translational psychiatry · 2026Article
- Hypnotic and sleep-promoting effects of Limosilactobacillus reuteri LM1063 on pentobarbital-induced sleep and electroencephalogram analysis in mice.Scientific reports · 2026Article
- Photomapping electrically coupled networks of the mature thalamus and cortex.bioRxiv : the preprint server for biology · 2026Article
- Implication of the thalamus in sleep alterations observed in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Nucleus Reuniens-Elicited Delta Oscillations Disable the Prefrontal Cortex in Schizophrenia.Cells · 2025Review
- Resolving native GABANature · 2025Article
- Evoked slow oscillations and dynamic network reorganization after stroke.Brain communications · 2025Article
- GABA system as the cause and effect in early development.Neuroscience and biobehavioral reviews · 2024Review
- Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease.Aging and disease · 2024Review
- Sleep-Deep-Learner is taught sleep-wake scoring by the end-user to complete each record in their style.Sleep advances : a journal of the Sleep Research Society · 2024Article
- Sleep-Deep-Net learns sleep wake scoring from the end-user and completes each record in their style.bioRxiv : the preprint server for biology · 2023Article
- Parvalbumin neurons in the anterior nucleus of thalamus control absence seizures.Epilepsia open · 2023Article
- Sleep-Enhancing Effect of Water Extract from Jujube (Foods (Basel, Switzerland) · 2023Article
- Biochemical pathways of sleep.Cell research · 2023Article
- Circuits and components of delta wave regulation.Brain research bulletin · 2022Review
- Alterations of sleep oscillations in Alzheimer's disease: A potential role for GABAergic neurons in the cortex, hippocampus, and thalamus.Brain research bulletin · 2022Review
- Translational approaches to influence sleep and arousal.Brain research bulletin · 2022Review
- Knockdown of GABANature communications · 2022Article
- The role of the GABAergic system on insomnia.Tzu chi medical journalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
David S UygunVA Boston Healthcare System and Harvard Medical School, Dept. of Psychiatry, West Roxbury, MA, 02132, USA.ORCID 0000-0002-6592-3223
Chun YangVA Boston Healthcare System and Harvard Medical School, Dept. of Psychiatry, West Roxbury, MA, 02132, USA.
Elena R TilliStonehill College, Department of Psychology, Easton, MA, 02357, USA.ORCID 0000-0002-9590-0444
Fumi KatsukiVA Boston Healthcare System and Harvard Medical School, Dept. of Psychiatry, West Roxbury, MA, 02132, USA.ORCID 0000-0002-1411-6317
Erik L HodgesVA Boston Healthcare System and Harvard Medical School, Dept. of Psychiatry, West Roxbury, MA, 02132, USA.ORCID 0000-0002-6123-3540
James T McKennaVA Boston Healthcare System and Harvard Medical School, Dept. of Psychiatry, West Roxbury, MA, 02132, USA.ORCID 0000-0002-9710-3553
James M McNallyVA Boston Healthcare System and Harvard Medical School, Dept. of Psychiatry, West Roxbury, MA, 02132, USA.ORCID 0000-0002-6043-8560
Ritchie E BrownVA Boston Healthcare System and Harvard Medical School, Dept. of Psychiatry, West Roxbury, MA, 02132, USA.ORCID 0000-0002-7164-4132
Radhika BasheerVA Boston Healthcare System and Harvard Medical School, Dept. of Psychiatry, West Roxbury, MA, 02132, USA. radhika_basheer@hms.harvard.edu.ORCID 0000-0002-4052-6897
Harvard University · USStonehill College · US
Funding
Research Education ComponentP30AG062421 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI STEVEN E ARNOLD · 2019 to 2026
$36.5MTRAINING IN SLEEP, CIRCADIAN &RESPIRATORY NEUROBIOLOGYT32HL007901 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Charles A Czeisler · 1998 to 2026
$18.5MTHE SYNAPTIC BASIS OF SLEEP CYCLE CONTROLR01MH039683 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI BROWN, RITCHIE EDWARD · 1985 to 2017
$3.8MTHE SYNAPTIC BASIS OF SLEEP CYCLE CONTROLR37MH039683 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MCCARLEY, ROBERT W · 1987 to 2006
$3.1MNeural Correlates of Sleep HomeostasisR01NS119227 · NINDS · HARVARD MEDICAL SCHOOL · PI BASHEER, RADHIKA · 2021 to 2025
$1.6MAlteration of sleep and cortical parvalbumin interneurons in mouse model of Alzheimers diseaseK01AG068366 · NIA · HARVARD MEDICAL SCHOOL · PI KATSUKI, FUMI · 2021 to 2025
$607kSubcortical influence on the respiratory coordination of cortical neurodynamicsrelated to cognitionR21MH125242 · NIMH · HARVARD MEDICAL SCHOOL · PI MCKENNA, JAMES TIMOTHY, MCNALLY, JAMES M · 2021 to 2022
$363kOptogenetic dissection of basal forebrain neurons involved in sleep homeostasisR21NS079866 · NINDS · HARVARD MEDICAL SCHOOL · PI BASHEER, RADHIKA · 2012 to 2013
$341kSleep Spindles: Role of Thalamic Reticular Nucleus and Parvalbumin GABA NeuronsI01BX001356 · VA · VA BOSTON HEALTH CARE SYSTEM · PI BROWN, RITCHIE EDWARD · 2012 to 2020
–Specification of sleep-wake control neurons in the basal forebrainI01BX004673 · VA · VA BOSTON HEALTH CARE SYSTEM · PI BROWN, RITCHIE EDWARD · 2020 to 2024
–Using CRISPR-Cas9 genetic abscission in vivo to study the role of GABA-A receptors of the thalamic reticular nucleus in regulating non-rapid-eye-movement sleep and drug induced sleepIK2BX004905 · VA · VA BOSTON HEALTH CARE SYSTEM · PI UYGUN, DAVID SAMUEL · 2020 to 2024
–Purinergic Mechanisms in Homeostatic Sleep ControlI01BX001404 · VA · VA BOSTON HEALTH CARE SYSTEM · PI BASHEER, RADHIKA · 2012 to 2021
–BLRD VA I01 BX001356BLRD VA I01 BX001404BLRD VA I01 BX004500BLRD VA I01 BX004673BLRD VA IK2 BX004905NHLBI NIH HHS T32 HL007901NIA NIH HHS K01 AG068366NIA NIH HHS P30 AG062421NIMH NIH HHS R01 MH039683NIMH NIH HHS R21 MH125242NIMH NIH HHS R37 MH039683NINDS NIH HHS R01 NS119227NINDS NIH HHS R21 NS079866
Abstract
Identification of mechanisms which increase deep sleep could lead to novel treatments which promote the restorative effects of sleep. Here, we show that knockdown of the α3 GABA
Indexed as
ParvalbuminsSleep, Slow-WaveAnimalsgamma-Aminobutyric AcidMiceNeuronsReceptors, GABA-AThalamusgamma-Aminobutyric AcidParvalbuminsReceptors, GABA-A
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.