Evidence map›Paper›PMID 35473858›Full record

ArticleAnalytica chimica acta2022

Evaluation of electropolymerized molecularly imprinted polymers (E-MIPs) on disposable electrodes for detection of SARS-CoV-2 in saliva.

H F El Sharif, S R Dennison, M Tully, S Crossley, W Mwangi, D Bailey, S P Graham, S M Reddy

Open access · hybridAbstract read
In one paragraph

Article in Analytica chimica acta, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 73 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

H F El SharifDepartment of Chemistry, UCLan Centre for Smart Materials, School of Natural Sciences, University of Central Lancashire, Preston, PR1 2HE, United Kingdom.
S R DennisonSchool of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, PR1 2HE, United Kingdom.
M TullyThe Pirbright Institute, Pirbright, Woking, Surrey, GU24 0NF, United Kingdom.
S CrossleyThe Pirbright Institute, Pirbright, Woking, Surrey, GU24 0NF, United Kingdom.
W MwangiThe Pirbright Institute, Pirbright, Woking, Surrey, GU24 0NF, United Kingdom.
D BaileyThe Pirbright Institute, Pirbright, Woking, Surrey, GU24 0NF, United Kingdom.
S P GrahamThe Pirbright Institute, Pirbright, Woking, Surrey, GU24 0NF, United Kingdom.
S M ReddyDepartment of Chemistry, UCLan Centre for Smart Materials, School of Natural Sciences, University of Central Lancashire, Preston, PR1 2HE, United Kingdom. Electronic address: smreddy@uclan.ac.uk.
The Pirbright Institute · GBUniversity of Lancashire · GB

Funding

Biotechnology and Biological Sciences Research Council BBS/E/I/00007034Biotechnology and Biological Sciences Research Council BBS/E/I/00007038Biotechnology and Biological Sciences Research Council BBS/E/I/00007039Biotechnology and Biological Sciences Research Council BBS/E/I/COV07001
6 · The paper itself

Abstract

We investigate electropolymerized molecularly imprinted polymers (E-MIPs) for the selective recognition of SARS-CoV-2 whole virus. E-MIPs imprinted with SARS-CoV-2 pseudoparticles (pps) were electrochemically deposited onto screen printed electrodes by reductive electropolymerization, using the water-soluble N-hydroxmethylacrylamide (NHMA) as functional monomer and crosslinked with N,N'-methylenebisacrylamide (MBAm). E-MIPs for SARS-CoV-2 showed selectivity for template SARS-CoV-2 pps, with an imprinting factor of 3:1, and specificity (significance = 0.06) when cross-reacted with other respiratory viruses. E-MIPs detected the presence of SARS-CoV-2 pps in <10 min with a limit of detection of 4.9 log

Indexed as

COVID-19Molecularly Imprinted PolymersAntibodies, ViralElectrodesHumansSalivaSARS-CoV-2State MedicineAntibodies, ViralMolecularly Imprinted PolymersBiosensorCOVID-19Electrochemical impedance spectroscopyElectrochemical polymerizationMolecularly imprinted polymersSARS-CoV-2

Identifiers

PMID35473858
PMCPMC8974637
OpenAlexW4220902536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.